The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
CHEMICAL MODIFICATION OF RAVIDOMYCIN AND EVALUATION OF BIOLOGICAL ACTIVITIES OF ITS DERIVATIVES
S. RAKHIT, C. ENG, H. BAKER, K. SINGH
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JOURNAL FREE ACCESS

1983 Volume 36 Issue 11 Pages 1490-1494

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Abstract

Several derivatives of the antitumor antibiotic ravidomycin were synthesized and their anti-tumor and antimicrobial activities and mode of action were evaluated. Deacylation produced a compound with higher biological activity than the parent. Structure-activity relationship of the derivatives is discussed.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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