METABOLIC PRODUCTS OF MICROORGANISMS 123THRAUSTOMYCIN, A NEW ANTIFUNGAL NUCLEOSIDE ANTIBIOTIC FROM STREPTOMYCES EXFOLIATUS

H. KNEIFEL; W. A. KÖNIG; G. WOLF; H. ZÃHNER

doi:10.7164/antibiotics.27.20

H. KNEIFEL, W. A. KÖNIG, G. WOLF, H. ZÃHNER

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JOURNAL FREE ACCESS

1974 Volume 27 Issue 1 Pages 20-27

DOI https://doi.org/10.7164/antibiotics.27.20

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Abstract

A new nucleoside antibiotic, inhibiting the growth of fungi, could be isolated from Streptomyces exfoliatus. The antibiotic was found by a screening method based on the inhibition of zygospore formation of Mucor hiemalis. It is composed of equal amounts of adenine, L-leucine, and an unusual tetrahydroxy-monocarbonic acid, C₁₁H₁₄O₉ with properties similar to a carbohydrate.

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