SFX by Ex Libris Inc.

Title:	dsAAV8-mediated gene transfer and β-cell expression of IL-4 and β-cell growth factors are capable of reversing early-onset diabetes in NOD mice
Source:	Gene Therapy [0969-7128] Gaddy, D F yr:2011

Basic

Full text

Full text available via Nature

Year:

Volume:

Issue:

Start Page:

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	Flores, R R. "Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells." Gene Therapy 21.8 (2014): 715-722.
description	2.	Sherry, Nicole A A. "Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells." Endocrinology 148.11 (2007): 5136-44.
description	3.	Johnson, Mark C. "β-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice." Diabetes 62.11 (2013): 3775-84.
description	4.	Burn, P. "The potential of incretin-based therapies in type 1 diabetes." Drug discovery today 17.1-2 (2011): 89-95.
description	5.	Zhang, J. "Continuous stimulation of human glucagon-like peptide-1 (7-36) amide in a mouse model (NOD) delays onset of autoimmune type 1 diabetes." Diabetologia 50.9 (2007): 1900-1909.
description	6.	Ueno A, Cho S, Cheng L, Wang J, Hou S, Nakano H, S, A. "Transient upregulation of IDO in dendritic cells by human chorionic gonadotropin downregulates autoimmune diabetes." Diabetes (2007): 1686-93.
description	7.	Dor, Y. "Recovery from diabetes in mice by beta cell regeneration." The journal of clinical investigation 117.9 (2007): 2553-61.
description	8.	Huurman, V A L L. "Differential inhibition of autoreactive memory- and alloreactive naive T cell responses by soluble cytotoxic T lymphocyte antigen 4 (s CTLA4), CTLA4Ig and LEA29Y." Clinical and experimental immunology 150.3 (2007): 487-493.
description	9.	Melton, Douglas A J. "Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver." Nature 445.7130 (2007): 886-91.
description	10.	Huurman, Volkert A L A. "Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients." Diabetes/metabolism research and reviews (2007): 269-75.
description	11.	Brennand, K. "All beta Cells Contribute Equally to Islet Growth and Maintenance." PLoS biology 5.7 (2007): 1520-1529.
description	12.	Dor, Y. "Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation." Nature 429.6987: 41-46.
description	13.	Roep, J W W. "Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men." Annals of the New York Academy of Sciences 1103.1 (2007): 192-5.
description	14.	D'Alessio, David A. "Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose." Diabetes 51.4 (2002): 951-957.
description	15.	Christoffersson, G. "VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue." Blood 120.23 (2012): 4653-62.
description	16.	Yanay, O. "Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide." The journal of gene medicine 12.6 (2010): 538-544.
description	17.	Wei^1, A.-H H. "Enhanced Differentiation of Human Adipose Tissue-derived Stromal Cells into Insulin-producing Cells with Glucagon-like Peptide-1." Experimental and clinical endocrinology & diabetes 120.1 (2012): 28-34.
description	18.	Bonner-Weir, S. "Beta-cell growth and regeneration: replication is only part of the story." Diabetes 59.10 (2010): 2340-2348.
description	19.	Krieg, C. "Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells." Proceedings of the National Academy of Sciences of the United States of America 107.26 (2010): 11906-11911.
description	20.	French, M B. "Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice." Diabetes 46.1 (1997): 34-39.