ExLibris header image
SFX Logo
Title: The B-RafV600E inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
Source:

Cell death & Disease [2041-4889] Li, J-X yr:2014


Collapse list of basic services Basic
Full text
Full text available via Nature
GO
Full text available via PubMed Central
GO
Document delivery
Request document via Library/Bibliothek GO
Users interested in this article also expressed an interest in the following:
1. "Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption." Chemico-biological interactions. 256: 266-273. Link to SFX for this item
2. Harris, Philip A. "Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis." ACS medicinal chemistry letters 4.12 (2013): 4294967295-1243. Link to Full Text for this item Link to SFX for this item
3. Kaiser, William J. "Viral modulation of programmed necrosis." Current Opinion in Virology 3.3 (2013): 296-306. Link to SFX for this item
4. "Necroptosis: The Trojan horse in cell autonomous antiviral host defense." Virology. 479-480: 160-166. Link to SFX for this item
5. "Three-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials." Eur J Cancer 82: 45-55. Link to SFX for this item
6. Su, B. "Template-Based de Novo Design for Type II Kinase Inhibitors and Its Extented Application to Acetylcholinesterase Inhibitors." Molecules 18.11: 13487-13509. Link to SFX for this item
7. Wang, Ming i. "The histone deacetylase inhibitor vorinostat prevents TNFα-induced necroptosis by regulating multiple signaling pathways." Apoptosis 18.11 (2013): 1348-1362. Link to Full Text for this item Link to SFX for this item
8. Berger, Scott B. "Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice." The journal of immunology 192.12 (2014): 5476-5480. Link to SFX for this item
9. Shiao, H. "Optimization of Ligand and Lipophilic Efficiency To Identify an in Vivo Active Furano-Pyrimidine Aurora Kinase Inhibitor." Journal of medicinal chemistry 56.13 (2013): 5247-5260. Link to Full Text for this item Link to SFX for this item
10. Van Hauwermeiren, F. "Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1." Cytokine & growth factor reviews 22.5 (2011): 311-319. Link to SFX for this item
11. William J. Kaiser; Jason W. Upton; Alyssa B. Long; Devon Livingston-Rosanoff; Lisa P. Daley-Bauer; Razqallah Hakem; Tamara Caspary; Edward S. Mocarski;, William J. "RIP3 mediates the embryonic lethality of caspase-8-deficient mice." Nature 471.7338 (2011): 368-372. Link to Full Text for this item Link to SFX for this item
12. Kufareva, I. "Type-II Kinase Inhibitor Docking, Screening, and Profiling Using Modified Structures of Active Kinase States." Journal of medicinal chemistry 51.24 (2008): 7921-7932. Link to Full Text for this item Link to SFX for this item
13. Gnther, C. "Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis." Nature 477.7364 (2011): 335-339. Link to Full Text for this item Link to SFX for this item
14. "Antiseptic effects of dabrafenib on TGFBIp-induced septic responses." Chemico-biological interactions. 278: 92-100. Link to SFX for this item
15. Long, J B A G V. "Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study." Annals of oncology : official journal of the European Society for Medical Oncology / 28.7: 1631-1639. Link to SFX for this item
16. Bugge, S. "Extended structure–activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties." European journal of medicinal chemistry 107 (2016): 255-274. Link to SFX for this item
17. Mehndiratta, S. "Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity." European journal of medicinal chemistry 85.15 (2014): 468-479. Link to SFX for this item
18. Lee, H. "1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors." ChemBioChem 14.10 (2013): 1248-1254. Link to Full Text for this item Link to SFX for this item
19. Xiao, M. "ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-κB pathway." Cellular physiology and biochemistry 32.6 (2013): 1587-99. Link to SFX for this item
20. Gamboa, O. "Budget Impact Analysis Of Tocilizumab In Rheumatoid Arthritis (Ra) In Colombia." Value in health 17.3 (2014). Link to Full Text for this item Link to SFX for this item
View More...
View Less...
Select All Clear All

Expand list of advanced services Advanced
A service provided by the Library of the Wissenschaftspark Albert Einstein, Potsdam, Germany.
© 2005 SFX by Ex Libris Inc.