Suprachiasmatic stimulation phase shifts rodent circadian rhythms

Science. 1982 Mar 12;215(4538):1407-9. doi: 10.1126/science.7063851.

Abstract

The integrity of the suprachiasmatic nuclei (SCN) of the hypothalamus is essential to the expression of normal circadian rhythms in rodents. Electrical stimulation of the SCN caused phase shifts and period changes in the freerunning feeding rhythms of rats and activity rhythms of hamsters. The phase response curve for SCN stimulation appears to parallel that for light pulses. These findings strengthen the hypothesis derived from lesion studies that the SCN are the dominant light-entrained oscillators in the rodent circadian system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials
  • Animals
  • Brain Mapping
  • Circadian Rhythm*
  • Electric Stimulation
  • Hypothalamus / physiology*
  • Neurons / physiology
  • Rats