Abstract
Plasma cholesterol sulfate concentration is increased in patients with recessive X-linked ichthyosis, a disease in which steroid sulfatase activity is absent. In these patients, cholesterol sulfate is found primarily in the low-density lipoprotein fraction of plasma, and the electrophoretic mobility of these lipoproteins is greatly increased.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Cholesterol Esters / blood*
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Electrophoresis, Agar Gel
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Female
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Genes, Recessive
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Genetic Linkage
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Humans
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Ichthyosis / blood
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Ichthyosis / genetics*
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Lipoproteins, LDL / blood*
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Steryl-Sulfatase
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Sulfatases / deficiency
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Sulfates
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X Chromosome
Substances
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Cholesterol Esters
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Lipoproteins, LDL
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Sulfates
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Sulfatases
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Steryl-Sulfatase