Sequential interaction of glia maturation factor with insulin

Science. 1984 Mar 30;223(4643):1419-20. doi: 10.1126/science.6367047.

Abstract

Astroblasts in culture proliferated when exposed to glia maturation factor for at least 2 hours and then to insulin, but not when exposed in the reverse order. The sequential relation suggests that glia maturation factor is a competence factor.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Astrocytes / drug effects
  • Astrocytes / physiology
  • Cell Division / drug effects
  • Cells, Cultured
  • Drug Interactions
  • Glia Maturation Factor
  • Growth Substances / pharmacology*
  • Growth Substances / physiology
  • Insulin / pharmacology*
  • Insulin / physiology
  • Mice
  • Mice, Inbred BALB C
  • Nerve Tissue Proteins / pharmacology*
  • Nerve Tissue Proteins / physiology
  • Rats

Substances

  • Glia Maturation Factor
  • Growth Substances
  • Insulin
  • Nerve Tissue Proteins