Abstract
17 beta-[16 alpha-125I]Iodoestradiol has been synthesized by exchange of 16 beta-bromoestradiol with Na125I. The iodinated product is readily separated from the bromo reactant by column chromatography. It concentrates in the rat uterus in vivo and binds avidly and specifically to the uterine estrogen receptor in vitro.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Animals
-
Estradiol / analogs & derivatives*
-
Estradiol / analysis
-
Estradiol / metabolism
-
Female
-
Iodine Radioisotopes
-
Radioimmunoassay / methods
-
Rats
-
Receptors, Estrogen / metabolism*
-
Uterus / metabolism
Substances
-
Iodine Radioisotopes
-
Receptors, Estrogen
-
Estradiol