Genes coding for histone proteins in man are located on the distal end of the long arm of chromosome 7

Science. 1979 Aug 31;205(4409):908-10. doi: 10.1126/science.472711.

Abstract

Tritium-labeled complementary RNA's to two cloned sea urchin DNA sequences, one coding for histones H1, H2B, and H4 and the other for H2A and H3, were hybridized in situ to high resolution human chromosomes. Evidence is presented showing that the histone genes in man are localized in bands q32-36 on the long arm of chromosome 7.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Mapping
  • Chromosomes / ultrastructure
  • Chromosomes, Human, 6-12 and X*
  • Genes*
  • Histones / genetics*
  • Humans
  • Lymphocytes / ultrastructure
  • Nucleic Acid Hybridization
  • Sea Urchins / genetics

Substances

  • Histones