The Drosophila genome sequence: implications for biology and medicine

Science. 2000 Mar 24;287(5461):2218-20. doi: 10.1126/science.287.5461.2218.

Abstract

The 120-megabase euchromatic portion of the Drosophila melanogaster genome has been sequenced. Because the genome is compact and many genetic tools are available, and because fly cell biology and development have much in common with mammals, this sequence may be the Rosetta stone for deciphering the human genome.

MeSH terms

  • Animals
  • Biology*
  • Cloning, Molecular
  • DNA Transposable Elements
  • Drosophila melanogaster / genetics*
  • Drosophila melanogaster / physiology
  • Genes, Insect
  • Genetics, Medical*
  • Genome*
  • Genome, Human*
  • Humans
  • Mutation
  • Physical Chromosome Mapping
  • Sequence Analysis, DNA*

Substances

  • DNA Transposable Elements