The 2023 MDPI Annual Report has
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17 pages, 721 KiB  
Article
New Fat Bases in Model Emulsion Systems in Physicochemical and Consumer Evaluation
by Małgorzata Kowalska, Magdalena Woźniak, Paweł Turek and Anna Żbikowska
Appl. Sci. 2024, 14(9), 3553; https://doi.org/10.3390/app14093553 (registering DOI) - 23 Apr 2024
Abstract
The purpose of this study was to indicate the validity of using enzymatically interesterified fats as a fat emulsion base. A study was conducted to determine the stability of emulsion systems based on enzymatically interesterified fats and fats containing mixed fats. The fats [...] Read more.
The purpose of this study was to indicate the validity of using enzymatically interesterified fats as a fat emulsion base. A study was conducted to determine the stability of emulsion systems based on enzymatically interesterified fats and fats containing mixed fats. The fats used in the modifications were mutton tallow and hemp oil. It was found that emulsions based on esterified fats, regardless of the type of modified fat, showed a higher shelf life and had high homogeneity. On the other hand, emulsions based on mixed fats already showed destabilization characteristics in the first days. Their structure was heterogeneous. Microscopic evaluation clearly showed large droplets of the dispersed phase, indicating a tendency to delaminate. Consumer evaluation showed that the sensory quality of the presented emulsion systems based on enzymatically interesterified fats was fully accepted by the participating consumers. Based on the results of the study, it was concluded that all of the consumer-evaluated emulsions received good or very good acceptance in terms of the sensory characteristics evaluated. Full article
(This article belongs to the Special Issue Advances in the Improvement of Colloidal Systems’ Stability)
15 pages, 10245 KiB  
Article
Monitoring Total Phosphorus Concentration in the Middle Reaches of the Yangtze River Using Sentinel-2 Satellites
by Fan Yang, Qi Feng, Yadong Zhou, Wen Li, Xiaoyang Zhang and Baoyin He
Remote Sens. 2024, 16(9), 1491; https://doi.org/10.3390/rs16091491 (registering DOI) - 23 Apr 2024
Abstract
Total phosphorus (TP, a non-optical sensitivity parameter) has become the primary pollutant in the Yangtze River, the third largest river in the world. It is strongly correlated with turbidity (an optical sensitivity parameter) in rivers. In this study, we constructed a turbidity-mediated TP [...] Read more.
Total phosphorus (TP, a non-optical sensitivity parameter) has become the primary pollutant in the Yangtze River, the third largest river in the world. It is strongly correlated with turbidity (an optical sensitivity parameter) in rivers. In this study, we constructed a turbidity-mediated TP retrieval model using Sentinel-2 observations and field-measured daily-scale water quality. The model was successfully applied to estimate the temporal and spatial variations of TP concentration in the middle reaches of the Yangtze River (MYR) from 2020 to 2023. Our results show: (1) the model accuracy of TP concentration retrieval with turbidity is significantly higher (R2 = 0.71, MAPE = 15.78%) than that for the model without turbidity (R2 = 0.62, MAPE = 16.38%); (2) the turbidity and TP concentration in the MYR is higher in summer and autumn than in winter and spring; and (3) the turbidity and total phosphorus (TP) concentration of the Yangtze River showed a significant increase after passing through Dongting Lake (p < 0.05). Full article
(This article belongs to the Special Issue Remote Sensing in Natural Resource and Water Environment II)
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23 pages, 1506 KiB  
Article
Systems Biology for Drug Target Discovery in Acute Myeloid Leukemia
by Svetlana Novikova, Tatiana Tolstova, Leonid Kurbatov, Tatiana Farafonova, Olga Tikhonova, Natalia Soloveva, Alexander Rusanov and Victor Zgoda
Int. J. Mol. Sci. 2024, 25(9), 4618; https://doi.org/10.3390/ijms25094618 (registering DOI) - 23 Apr 2024
Abstract
Combining new therapeutics with all-trans-retinoic acid (ATRA) could improve the efficiency of acute myeloid leukemia (AML) treatment. Modeling the process of ATRA-induced differentiation based on the transcriptomic profile of leukemic cells resulted in the identification of key targets that can be [...] Read more.
Combining new therapeutics with all-trans-retinoic acid (ATRA) could improve the efficiency of acute myeloid leukemia (AML) treatment. Modeling the process of ATRA-induced differentiation based on the transcriptomic profile of leukemic cells resulted in the identification of key targets that can be used to increase the therapeutic effect of ATRA. The genome-scale transcriptome analysis revealed the early molecular response to the ATRA treatment of HL-60 cells. In this study, we performed the transcriptomic profiling of HL-60, NB4, and K562 cells exposed to ATRA for 3-72 h. After treatment with ATRA for 3, 12, 24, and 72 h, we found 222, 391, 359, and 1032 differentially expressed genes (DEGs) in HL-60 cells, as well as 641, 1037, 1011, and 1499 DEGs in NB4 cells. We also found 538 and 119 DEGs in K562 cells treated with ATRA for 24 h and 72 h, respectively. Based on experimental transcriptomic data, we performed hierarchical modeling and determined cyclin-dependent kinase 6 (CDK6), tumor necrosis factor alpha (TNF-alpha), and transcriptional repressor CUX1 as the key regulators of the molecular response to the ATRA treatment in HL-60, NB4, and K562 cell lines, respectively. Mapping the data of TMT-based mass-spectrometric profiling on the modeling schemes, we determined CDK6 expression at the proteome level and its down-regulation at the transcriptome and proteome levels in cells treated with ATRA for 72 h. The combination of therapy with a CDK6 inhibitor (palbociclib) and ATRA (tretinoin) could be an alternative approach for the treatment of acute myeloid leukemia (AML). Full article
(This article belongs to the Collection Feature Paper Collection in Biochemistry)
19 pages, 10777 KiB  
Article
Effects of Different Drying Methods on Drying Characteristics, Microstructure, Quality, and Energy Consumption of Apricot Slices
by Qiaonan Yang, Xiaokang Yi, Hongwei Xiao, Xufeng Wang, Lin Liu, Ziya Tang, Can Hu and Xibing Li
Foods 2024, 13(9), 1295; https://doi.org/10.3390/foods13091295 (registering DOI) - 23 Apr 2024
Abstract
An appropriate drying method is crucial for producing high-quality dried apricots. In this study, the effects of four drying methods, hot air drying (HAD), infrared drying (IRD), pulse vacuum drying (PVD), and vacuum freeze-drying (VFD), on the drying kinetics and physical and nutritional [...] Read more.
An appropriate drying method is crucial for producing high-quality dried apricots. In this study, the effects of four drying methods, hot air drying (HAD), infrared drying (IRD), pulse vacuum drying (PVD), and vacuum freeze-drying (VFD), on the drying kinetics and physical and nutritional characteristics of apricot slices were evaluated. PVD required the shortest time (16.25 h), followed by IRD (17.54 h), HAD (21.39 h), and VFD (34.64 h). VFD resulted in the best quality of apricot slices, with the smallest color difference (ΔE = 13.64), lowest water activity (0.312 ± 0.015) and browning degree (0.35), highest color saturation (62.84), lowest hardness (8.35 ± 0.47 N) and shrinkage (9.13 ± 0.65%), strongest rehydration ability (3.58 ± 0.11 g/g), a good microstructure, and high nutrient-retention rates (ascorbic acid content: 53.31 ± 0.58 mg/100 g, total phenolic content: 12.64 ± 0.50 mg GAE/g, and carotenoid content: 24.23 ± 0.58 mg/100 g) and antioxidant activity (DPPH: 21.10 ± 0.99 mmol Trolox/g and FRAP: 34.10 ± 0.81 mmol Trolox/g). The quality of PVD-treated apricot slices was second-best, and the quality of HAD-treated apricot slices was the worst. However, the energy consumption required for VFD was relatively high, while that required for PVD was lower. The results of this study provide a scientific basis for the large-scale industrial production of dried apricots. Full article
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13 pages, 2584 KiB  
Article
Antibacterial, Anti-Biofilm, and Anti-Inflammatory Properties of Gelatin–Chitosan–Moringa-Biopolymer-Based Wound Dressings towards Staphylococcus aureus and Escherichia coli
by Salma Bessalah, Asim Faraz, Mohamed Dbara, Touhami Khorcheni, Mohamed Hammadi, Daniel Jesuwenu Ajose and Shamsaldeen Ibrahim Saeed
Pharmaceuticals 2024, 17(5), 545; https://doi.org/10.3390/ph17050545 (registering DOI) - 23 Apr 2024
Abstract
In contemporary times, the sustained aspiration of bioengineering and biomedical applications is the progressive advancement of materials characterized by biocompatibility and biodegradability. The investigation of the potential applications of polymers as natural and non-hazardous materials has placed significant emphasis on their physicochemical properties. [...] Read more.
In contemporary times, the sustained aspiration of bioengineering and biomedical applications is the progressive advancement of materials characterized by biocompatibility and biodegradability. The investigation of the potential applications of polymers as natural and non-hazardous materials has placed significant emphasis on their physicochemical properties. Thus, this study was designed to investigate the potential of gelatin–chitosan–moringa leaf extract (G–CH–M) as a novel biomaterial for biomedical applications. The wound-dressing G–CH–M biopolymer was synthesized and characterized. The blood haemolysis, anti-inflammatory, antioxidant, and antibacterial activities of the biopolymer were investigated against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial isolates. Our results showed that S. aureus swarming motility was drastically affected. However, the biopolymer had no significant effect on the swarming motility of E. coli. In addition, the biopolymer showed high antibacterial capacities, especially against S. aureus. Plasmid DNA was observed to be effectively protected from oxidative stresses by the biopolymer. Furthermore, the biopolymer exhibited greatly suppressed haemolysis (lower than 2%), notwithstanding the elevated concentration of 50 mg/mL. These results indicated that this novel biopolymer formulation could be further developed for wound care and contamination prevention. Full article
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23 pages, 2546 KiB  
Article
Optimal Placement of Sensors in Traffic Networks Using Global Search Optimization Techniques Oriented towards Traffic Flow Estimation and Pollutant Emission Evaluation
by Gianfranco Gagliardi, Vincenzo Gallelli, Antonio Violi, Marco Lupia and Gianni Cario
Sustainability 2024, 16(9), 3530; https://doi.org/10.3390/su16093530 (registering DOI) - 23 Apr 2024
Abstract
The relationship between estimating traffic flow and evaluating pollutant emissions lies in understanding how vehicular traffic patterns affect air quality. Traffic flow estimation is a complex field that involves a variety of analytical techniques to understand, predict, and manage the flow of vehicles [...] Read more.
The relationship between estimating traffic flow and evaluating pollutant emissions lies in understanding how vehicular traffic patterns affect air quality. Traffic flow estimation is a complex field that involves a variety of analytical techniques to understand, predict, and manage the flow of vehicles on road networks. Different types of analyses commonly employed in this area are statistical analysis (e.g., descriptive statistics, inferential statistics, time series analysis), mathematical modeling (macroscopic models, microscopic models, mesoscopic models), computational methods (e.g., simulation modeling, machine learning, and AI techniques), geospatial analysis (e.g., geographic information systems (GISs), spatial data analysis), network analysis (e.g., graph theory and network flow models). In sensor network setups, the strategic placement of sensors is crucial, primarily due to the challenges posed by limited energy supplies, restricted storage capabilities, and the demands on processing and communication, all of which significantly impact maintenance costs and hardware limitations. To mitigate the burden on processing and communication, it is essential to deploy a limited number of sensors strategically. In practical applications, achieving an optimal layout of physical sensors (i.e., placing sensors within the network in such a way as to meet a specific optimality criterion, such as identifying the minimum number of sensors required to ensure the ability to design reliable state observers capable of reconstructing the network’s state based on the available data) is essential for the accurate monitoring of large-scale systems, including traffic flow or the distribution networks of water and gas. In the context of traffic systems, addressing the challenge of full link flow observability, that is, the ability to accurately monitor and assess the flow of entities (i.e., vehicles) across all the links or pathways within a network, entails selecting the smallest number of traffic sensors from a larger set to install. The goal is to choose a subset of p sensors, which may include redundancies, from a pool of n>>p potential sensors. This is conducted to maintain the structural observability of the entire traffic network. This concept pertains to deducing the complete internal state (traffic volume on each road link in the network) from external outputs and inputs (measurements from sensors). The traditional concept of system observability serves as a criterion for sensor placement. This article presents the development of a simulated annealing heuristic to address the selection problem. The selected sensors are then applied to construct a Luenberger observer, a mathematical construct used in control theory to accurately estimate the internal state of a dynamic system based on its inputs and outputs. Numerical simulations are carried out to demonstrate the effectiveness of this method, and a performance analysis using a digital twin of a transport network, designed using the Aimsun Next software, are also carried out to assess traffic flow and associated pollutant emissions. In particular, we examine a traffic network comprising 21 roads. We address the sensor selection problem by identifying an optimal set of six sensors, which facilitates the design of a Luenberger observer. This observer enables the reconstruction of traffic flow across the network with minimal estimation error. Furthermore, by integrating this observer with data from the Aimsun Next software, we assess the pollutant emissions related to traffic flow. The results indicate a high accuracy in estimating pollutant levels. Full article
18 pages, 4275 KiB  
Article
Conjugate Heat Transfer Advancements and Applications in Aerospace Engine Technology
by Hao Zha, Yaqian Xu, Zhigong Tang, Bin Li and Dongzhi Wang
Appl. Sci. 2024, 14(9), 3556; https://doi.org/10.3390/app14093556 (registering DOI) - 23 Apr 2024
Abstract
Over the past few decades, conjugate heat transfer (CHT) technology has been instrumental in predicting temperature fields within aerospace engines, guiding engine design with its predictive capabilities. This paper comprehensively surveys the foundational technologies of CHT and their applications in engine design, backed [...] Read more.
Over the past few decades, conjugate heat transfer (CHT) technology has been instrumental in predicting temperature fields within aerospace engines, guiding engine design with its predictive capabilities. This paper comprehensively surveys the foundational technologies of CHT and their applications in engine design, backed by an extensive literature review. A novel coupling iteration methodology, su-F-TFTB, was proposed. Following this, it introduced grid splicing technology tailored for heat flux conservation, which significantly enhances the adaptability of CHT grids. Ultimately, this study employed the self-developed Aerospace Engine Numerical Simulation (AENS v4.0.1) software to perform CHT analyses on NASA-C3X turbine blades equipped with ten radial cooling systems. A comparative analysis of pressure distributions across various density meshes was undertaken to affirm mesh independence. Furthermore, the impacts of the Spalart–Allmaras (SA) one-equation model and k–ω Shear Stress Transport (SST) two-equation model on the temperature distribution in conjugate heat transfer were investigated. The results indicated that the k–ω SST model exhibited superior performance, aligning closely with NASA experimental data. This validation confirmed the effectiveness of the software. Full article
(This article belongs to the Topic Advanced Heat and Mass Transfer Technologies)
15 pages, 640 KiB  
Article
Influence of Transport Distance, Animal Weight, and Muscle Position on the Quality Factors of Meat of Young Bulls during the Summer Months
by Alejandro Poveda-Arteaga, Alexander Bobe, Johannes Krell, Volker Heinz, Nino Terjung, Igor Tomasevic and Monika Gibis
Appl. Sci. 2024, 14(9), 3557; https://doi.org/10.3390/app14093557 (registering DOI) - 23 Apr 2024
Abstract
This study investigated the potential effects of transport distance, animal weight, and muscle position on meat quality in young bulls under commercial conditions across four slaughtering weeks during the summer months (May to September). Data on transport distance, lairage time, and ambient temperature [...] Read more.
This study investigated the potential effects of transport distance, animal weight, and muscle position on meat quality in young bulls under commercial conditions across four slaughtering weeks during the summer months (May to September). Data on transport distance, lairage time, and ambient temperature during slaughtering days were collected from 80 young bulls from North German farms. Meat quality parameters, including pH, temperature, and meat color were also recorded at several post-mortem times from two different carcass locations (shoulder clod and silverside). Meat texture was evaluated both by sensory and instrumental analysis, and their values were compared to find possible correlations between them. All of the aforementioned main factors (transport distance, animal weight, and muscle position), as well as the interaction between animal weight and transport distance, significantly influenced (p < 0.01) meat quality traits. The results of the assessment of the meat texture from the cooked meat patties suggested that silverside cuts were consistently harder than shoulder clod cuts, despite having lower pH48 values. Full article
(This article belongs to the Special Issue Advances in Meat Quality and Processing)
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5 pages, 1128 KiB  
Editorial
Catalytic Epoxidation Reaction
by Sébastien Leveneur, Pasi Tolvanen and Vincenzo Russo
Catalysts 2024, 14(5), 285; https://doi.org/10.3390/catal14050285 (registering DOI) - 23 Apr 2024
Abstract
The epoxidation of unsaturated groups is a well-known process [...] Full article
(This article belongs to the Special Issue Catalytic Epoxidation Reaction)
33 pages, 2107 KiB  
Article
Geometric Control and Structure-at-Infinity Control for Disturbance Rejection and Fault Compensation Regarding Buck Converter-Based LED Driver
by Jesse Y. Rumbo-Morales, Jair Gómez-Radilla, Gerardo Ortiz-Torres, Felipe D. J. Sorcia-Vázquez, Hector M. Buenabad-Arias, Maria A. López-Osorio, Carlos A. Torres-Cantero, Moises Ramos-Martinez, Mario A. Juárez, Manuela Calixto-Rodriguez, Jorge A. Brizuela-Mendoza and Jesús E. Valdez-Resendiz
Mathematics 2024, 12(9), 1277; https://doi.org/10.3390/math12091277 (registering DOI) - 23 Apr 2024
Abstract
Currently, various light-emitting diode (LED) lighting systems are being developed because LEDs are one of the most used lighting sources for work environments, buildings, homes, and public roads in terms of some of their applications. Similarly, they have low energy consumption, quick responses, [...] Read more.
Currently, various light-emitting diode (LED) lighting systems are being developed because LEDs are one of the most used lighting sources for work environments, buildings, homes, and public roads in terms of some of their applications. Similarly, they have low energy consumption, quick responses, and excellent optimal performance in their operation. However, these systems still need to precisely regulate lighting, maintain stable voltage and current in the presence of faults and disturbances, and have a wide range of operations in the event of trajectory changes or monitoring tasks regarding the desired voltage and current. This work presents the design and application of two types of robust controllers (structure-at-infinity control and geometric control) applied to an LED driver using a buck converter. The controllers aim to follow the desired trajectories, attenuate disturbances at the power supply input, and compensate for faults in the actuator (MOSFET) to keep the capacitor voltage and inductor current stable. When comparing the results obtained with the two controllers, it was observed that both present excellent performance in the presence of constant disturbances. However, in scenarios in which variable faults and path changes are implemented, the structure-at-infinity control method shows an overimpulse of output voltage and current ranging from 39 to 42 volts and from 0.3 to 0.45 A, with a margin of error of 1%, and it can generate a failure in the LED driver using a buck converter. On the other hand, when using geometric control, the results are satisfactory, achieving attenuating constant disturbances and variable faults, reaching the desired voltage (40 v to 35 v) and current (0.3 to 0.25 A) with a margin of error of 0.05%, guaranteeing a system without overvoltages or the accelerated degradation of the components due to magnetic conductivity. Full article
(This article belongs to the Special Issue System Modeling, Control Theory, and Their Applications)
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27 pages, 6043 KiB  
Article
Beacon, a Lightweight Deep Reinforcement Learning Benchmark Library for Flow Control
by Jonathan Viquerat, Philippe Meliga, Pablo Jeken-Rico and Elie Hachem
Appl. Sci. 2024, 14(9), 3561; https://doi.org/10.3390/app14093561 (registering DOI) - 23 Apr 2024
Abstract
Recently, the increasing use of deep reinforcement learning for flow control problems has led to a new area of research focused on the coupling and adaptation of the existing algorithms to the control of numerical fluid dynamics environments. Although still in its infancy, [...] Read more.
Recently, the increasing use of deep reinforcement learning for flow control problems has led to a new area of research focused on the coupling and adaptation of the existing algorithms to the control of numerical fluid dynamics environments. Although still in its infancy, the field has seen multiple successes in a short time span, and its fast development pace is certainly partly imparted by the open-source effort that drives the expansion of the community. Yet this emerging domain is still missing a common ground to (i) ensure the reproducibility of the results and (ii) offer a proper ad hoc benchmarking basis. To this end, we propose beacon, an open-source benchmark library composed of seven lightweight one-dimensional and two-dimensional flow control problems with various characteristics, action and observation space characteristics, and CPU requirements. In this contribution, the seven considered problems are described, and reference control solutions are provided. The sources for the following work are publicly available. Full article
(This article belongs to the Special Issue Advances in Active and Passive Techniques for Fluid Flow Manipulation)
22 pages, 8187 KiB  
Article
A Systematic Investigation into the Optimization of Reactive Power in Distribution Networks Using the Improved Sparrow Search Algorithm–Particle Swarm Optimization Algorithm
by Yonggang Wang, Fuxian Li, Ruimin Xiao and Nannan Zhang
Energies 2024, 17(9), 2001; https://doi.org/10.3390/en17092001 (registering DOI) - 23 Apr 2024
Abstract
With the expansion of the scale of electric power, high-quality electrical energy remains a crucial aspect of power system management and operation. The generation of reactive power is the primary cause of the decline in electrical energy quality. Therefore, optimization of reactive power [...] Read more.
With the expansion of the scale of electric power, high-quality electrical energy remains a crucial aspect of power system management and operation. The generation of reactive power is the primary cause of the decline in electrical energy quality. Therefore, optimization of reactive power in the power system becomes particularly important. The primary objective of this article is to create a multi-objective reactive power optimization (MORPO) model for distribution networks. The model aims to minimize reactive power loss, reduce the overall compensation required for reactive power devices, and minimize the total sum of node voltage deviations. To tackle the MORPO problems for distribution networks, the improved sparrow search algorithm–particle swarm optimization (ISSA-PSO) algorithm is proposed. Specifically, two improvements are proposed in this paper. The first is to introduce a chaotic mapping mechanism to enhance the diversity of the population during initialization. The second is to introduce a three-stage differential evolution mechanism to improve the global exploration capability of the algorithm. The proposed algorithm is tested on the IEEE 33-node system and the practical 22-node system. The results indicate a reduction of 32.71% in network losses for the IEEE 33-node system after optimization, and the average voltage of the circuit increases from 0.9485 p.u. to 0.9748 p.u. At the same time, optimization results in a reduction of 44.07% in network losses for the practical 22-node system, and the average voltage of the circuit increases from 0.9838 p.u. to 0.9921 p.u. Therefore, the proposed method exhibits better performance for reducing network losses and enhancing voltage levels. Full article
(This article belongs to the Section F: Electrical Engineering)
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13 pages, 5556 KiB  
Article
Evaluation of Low-Cost CO2 Sensors Using Reference Instruments and Standard Gases for Indoor Use
by Qixiang Cai, Pengfei Han, Guang Pan, Chi Xu, Xiaoyu Yang, Honghui Xu, Dongde Ruan and Ning Zeng
Sensors 2024, 24(9), 2680; https://doi.org/10.3390/s24092680 (registering DOI) - 23 Apr 2024
Abstract
CO2 monitoring is important for carbon emission evaluation. Low-cost and medium-precision sensors (LCSs) have become an exploratory direction for CO2 observation under complex emission conditions in cities. Here, we used a calibration method that improved the accuracy of SenseAir K30 CO [...] Read more.
CO2 monitoring is important for carbon emission evaluation. Low-cost and medium-precision sensors (LCSs) have become an exploratory direction for CO2 observation under complex emission conditions in cities. Here, we used a calibration method that improved the accuracy of SenseAir K30 CO2 sensors from ±30 ppm to 0.7–4.0 ppm for a CO2-monitoring instrument named the SENSE-IAP, which has been used in several cities, such as in Beijing, Jinan, Fuzhou, Hangzhou, and Wuhan, in China since 2017. We conducted monthly to yearly synchronous observations using the SENSE-IAP along with reference instruments (Picarro) and standard gas to evaluate the performance of the LCSs for indoor use with relatively stable environments. The results show that the precision and accuracy of the SENSE-IAP compared to the standard gases were rather good in relatively stable indoor environments, with the short-term (daily scale) biases ranging from −0.9 to 0.2 ppm, the root mean square errors (RMSE) ranging from 0.7 to 1.6 ppm, the long-term (monthly scale) bias ranging from −1.6 to 0.5 ppm, and the RMSE ranging from 1.3 to 3.2 ppm. The accuracy of the synchronous observations with Picarro was in the same magnitude, with an RMSE of 2.0–3.0 ppm. According to our evaluation, standard instruments or reliable standard gases can be used as a reference to improve the accuracy of the SENSE-IAP. If calibrated daily using standard gases, the bias of the SENSE-IAP can be maintained within 1.0 ppm. If the standard gases are hard to access frequently, we recommend a calibration frequency of at least three months to maintain an accuracy within 3 ppm. Full article
(This article belongs to the Special Issue Advanced Sensors for Gas Monitoring)
23 pages, 1592 KiB  
Article
Prediction of the Properties of Vibro-Centrifuged Variatropic Concrete in Aggressive Environments Using Machine Learning Methods
by Alexey N. Beskopylny, Sergey A. Stel’makh, Evgenii M. Shcherban’, Irina Razveeva, Alexey Kozhakin, Anton Pembek, Tatiana N. Kondratieva, Diana Elshaeva, Andrei Chernil’nik and Nikita Beskopylny
Buildings 2024, 14(5), 1198; https://doi.org/10.3390/buildings14051198 (registering DOI) - 23 Apr 2024
Abstract
In recent years, one of the most promising areas in modern concrete science and the technology of reinforced concrete structures is the technology of vibro-centrifugation of concrete, which makes it possible to obtain reinforced concrete elements with a variatropic structure. However, this area [...] Read more.
In recent years, one of the most promising areas in modern concrete science and the technology of reinforced concrete structures is the technology of vibro-centrifugation of concrete, which makes it possible to obtain reinforced concrete elements with a variatropic structure. However, this area is poorly studied and there is a serious deficiency in both scientific and practical terms, expressed in the absence of a systematic knowledge of the life cycle management processes of vibro-centrifuged variatropic concrete. Artificial intelligence methods are seen as one of the most promising methods for improving the process of managing the life cycle of such concrete in reinforced concrete structures. The purpose of the study is to develop and compare machine learning algorithms based on ridge regression, decision tree and extreme gradient boosting (XGBoost) for predicting the compressive strength of vibro-centrifuged variatropic concrete using a database of experimental values obtained under laboratory conditions. As a result of laboratory tests, a dataset of 664 samples was generated, describing the influence of aggressive environmental factors (freezing–thawing, chloride content, sulfate content and number of wetting–drying cycles) on the final strength characteristics of concrete. The use of analytical techniques to extract additional knowledge from data contributed to improving the resulting predictive properties of machine learning models. As a result, the average absolute percentage error (MAPE) for the best XGBoost algorithm was 2.72%, mean absolute error (MAE) = 1.134627, mean squared error (MSE) = 4.801390, root-mean-square error (RMSE) = 2.191208 and R2 = 0.93, which allows to conclude that it is possible to use “smart” algorithms to improve the life cycle management process of vibro-centrifuged variatropic concrete, by reducing the time required for the compressive strength assessment of new structures. Full article
(This article belongs to the Section Building Materials, and Repair & Renovation)
14 pages, 801 KiB  
Article
Impact of Teaching and Learning Modes on Graduates’ Social and Entrepreneurial Skills Development: A Comparative Analysis
by Ana Tecilazić, Ivana Ogrizek Biškupić and Mislav Balković
Educ. Sci. 2024, 14(5), 443; https://doi.org/10.3390/educsci14050443 (registering DOI) - 23 Apr 2024
Abstract
There is a growing interest in researching the impact of different modes of learning and teaching on the non-academic outcomes of graduates, such as their employment outcomes. This study examines the impact of teaching and learning modes on the perceived relevance of study [...] Read more.
There is a growing interest in researching the impact of different modes of learning and teaching on the non-academic outcomes of graduates, such as their employment outcomes. This study examines the impact of teaching and learning modes on the perceived relevance of study programmes in preparing graduates for career entry and the development of social and entrepreneurial skills in six European countries that participated in the Eurograduate pilot survey: Austria, Croatia, Czechia, Lithuania, Malta, and Norway. The study shows that learning and teaching methods have a modest impact on graduates’ perceptions that their study programmes provide a good foundation for entering professional life. However, it proves that there is a significant relationship emerging between activating teaching and learning modes and the development of graduates’ social and entrepreneurial skills. It, thus, expands on the results of the first European pilot study on the graduate survey and contributes to the current debates in this area. Full article
17 pages, 554 KiB  
Article
12-Month Trajectories of Health-Related Quality of Life Following Hospitalization in German Cancer Centers—A Secondary Data Analysis
by Martin Eichler, Klaus Hönig, Corinna Bergelt, Hermann Faller, Imad Maatouk, Beate Hornemann, Barbara Stein, Martin Teufel, Ute Goerling, Yesim Erim, Franziska Geiser, Alexander Niecke, Bianca Senf and Joachim Weis
Curr. Oncol. 2024, 31(5), 2376-2392; https://doi.org/10.3390/curroncol31050177 (registering DOI) - 23 Apr 2024
Abstract
Patient-reported outcomes (PROs) offer a diverse array of potential applications within medical research and clinical practice. In comparative research, they can serve as tools for delineating the trajectories of health-related quality of life (HRQoL) across various cancer types. We undertook a secondary data [...] Read more.
Patient-reported outcomes (PROs) offer a diverse array of potential applications within medical research and clinical practice. In comparative research, they can serve as tools for delineating the trajectories of health-related quality of life (HRQoL) across various cancer types. We undertook a secondary data analysis of a cohort of 1498 hospitalized cancer patients from 13 German cancer centers. We assessed the Physical and Mental Component Scores (PCS and MCS) of the 12-Item Short-Form Health Survey at baseline (t0), 6 (t1), and 12 months (t2), using multivariable generalized linear regression models. At baseline, the mean PCS and MCS values for all cancer patients were 37.1 and 44.3 points, respectively. We observed a significant improvement in PCS at t2 and in MCS at t1. The most substantial and significant improvements were noted among patients with gynecological cancers. We found a number of significant differences between cancer types at baseline, t1, and t2, with skin cancer patients performing best across all time points and lung cancer patients performing the worst. MCS trajectories showed less pronounced changes and differences between cancer types. Comparative analyses of HRQoL scores across different cancer types may serve as a valuable tool for enhancing health literacy, both among the general public and among cancer patients themselves. Full article
11 pages, 363 KiB  
Article
Effectiveness of Mentorship Using Cognitive Behavior Therapy to Reduce Burnout and Turnover among Nurses: Intervention Impact on Mentees
by Takashi Ohue and Masaru Menta
Nurs. Rep. 2024, 14(2), 1026-1036; https://doi.org/10.3390/nursrep14020077 (registering DOI) - 23 Apr 2024
Abstract
Objective: Mentoring programs can improve nurses’ mental health. This study examined the effects of a staff training program based on cognitive behavior therapy for burnout in which mentors provided intervention to their mentees. Methods: The principal investigator served as a facilitator and conducted [...] Read more.
Objective: Mentoring programs can improve nurses’ mental health. This study examined the effects of a staff training program based on cognitive behavior therapy for burnout in which mentors provided intervention to their mentees. Methods: The principal investigator served as a facilitator and conducted staff training in cognitive behavior therapy. An original cognitive behavior therapy manual was presented to trained nurses (mentors), and lectures were provided on using the manual, ways of implementing cognitive behavior therapy, and other important points. The study participants included 35 mid-career nurses (mentors) and 34 young nurses in their first to third year (mentees) working in acute care hospitals. Groups of five mentees were formed in which two mentors provided cognitive behavior therapy based on the manual. Changes in mentees’ stress, burnout, and turnover intention at pre-intervention, post-intervention, and follow-up (3 months after the intervention) were objectively evaluated using an evaluation index. Results: The intervention significantly reduced the following evaluation indicators: total strain, conflict with other nursing staff, nursing role conflict, qualitative workload, quantitative workload, conflict with patients, problem avoidance due to irrational beliefs, escape-avoidance, emotional exhaustion of burnout, desire to change hospitals or departments, and turnover intention. Conclusion: Implementation of cognitive behavior therapy by mentors effectively reduced mentees’ stress, burnout, and turnover. Full article
(This article belongs to the Special Issue Burnout and Nursing Care)
15 pages, 1519 KiB  
Article
The Contribution of Genetic Testing in Optimizing Therapy for Patients with Recurrent Depressive Disorder
by Rita Ioana Platona, Florica Voiță-Mekeres, Cristina Tudoran, Mariana Tudoran and Virgil Radu Enătescu
Clin. Pract. 2024, 14(3), 703-717; https://doi.org/10.3390/clinpract14030056 (registering DOI) - 23 Apr 2024
Abstract
(1) Background: The aim of this study was to analyze the impact of pharmacogenetic-guided antidepressant therapy on the 12-month evolution of the intensity of depressive symptoms in patients with recurrent depressive disorder (RDD) in comparison to a control group of depressive subjects who [...] Read more.
(1) Background: The aim of this study was to analyze the impact of pharmacogenetic-guided antidepressant therapy on the 12-month evolution of the intensity of depressive symptoms in patients with recurrent depressive disorder (RDD) in comparison to a control group of depressive subjects who were treated conventionally. (2) Methods: This prospective longitudinal study was conducted between 2019 and 2022, and the patients were evaluated by employing the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A) and the Clinical Global Impressions Scale: Severity and Improvement. We followed them up at 1, 3, 6, and 12 months. (3) Results: Of the 76 patients with RDD, 37 were tested genetically (Group A) and 39 were not (Group B). Although the patients from Group A had statistically significantly more severe MDD at baseline than those from Group B (p < 0.001), by adjusting their therapy according to the genetic testing, they had a progressive and more substantial reduction in the severity of RDD symptoms [F = 74.334; η2 = 0.674; p < 0.001], indicating a substantial association with the results provided by the genetic testing (67.4%). (4) Conclusions: In patients with RDD and a poor response to antidepressant therapy, pharmacogenetic testing allows for treatment adjustment, resulting in a constant and superior reduction in the intensity of depression and anxiety symptoms. Full article
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17 pages, 387 KiB  
Article
Key Challenges of Cloud Computing Resource Allocation in Small and Medium Enterprises
by Abdulghafour Mohammad and Yasir Abbas
Digital 2024, 4(2), 372-388; https://doi.org/10.3390/digital4020018 (registering DOI) - 23 Apr 2024
Abstract
Although cloud computing offers many benefits, such as flexibility, scalability, and profitability, some small and medium enterprises (SMEs) are still unable to fully utilize cloud resources, such as memory, computing power, storage, and network bandwidth. This reduces their productivity and increases their expenses. [...] Read more.
Although cloud computing offers many benefits, such as flexibility, scalability, and profitability, some small and medium enterprises (SMEs) are still unable to fully utilize cloud resources, such as memory, computing power, storage, and network bandwidth. This reduces their productivity and increases their expenses. Therefore, the central objective of this paper was to examine the key challenges related to the allocation of cloud computing resources in small and medium enterprises. The method used for this study is based upon qualitative research using 12 interviews with 12 owners, managers, and experts in cloud computing in four countries: the United States of America, the United Kingdom, India, and Pakistan. Our results, based on our empirical data, show 11 key barriers to resource allocation in cloud computing that are classified based on the technology, organization, and environment (TOE) framework. Theoretically, this research contributes to the body of knowledge concerning cloud computing technology and offers valuable understanding of the cloud computing resource allocation approaches employed by small and medium enterprises (SMEs). In practice, this research is useful to aid SMEs in implementing successful and sustainable strategies for allocating cloud computing resources. Full article
19 pages, 4730 KiB  
Article
Exchangeable Quantities and Power Laws: Τhe Case of Pores in Solids
by Antigoni G. Margellou and Philippos J. Pomonis
Foundations 2024, 4(2), 156-174; https://doi.org/10.3390/foundations4020012 (registering DOI) - 23 Apr 2024
Abstract
In this work we suggest that the common cause for the development of various power laws is the existence of a suitable exchangeable quantity between the agents of a set. Examples of such exchangeable quantities, leading to eponymous power laws, include money (Pareto’s [...] Read more.
In this work we suggest that the common cause for the development of various power laws is the existence of a suitable exchangeable quantity between the agents of a set. Examples of such exchangeable quantities, leading to eponymous power laws, include money (Pareto’s Law), scientific knowledge (Lotka’s Law), people (Auerbach’s Law), and written or verbal information (Zipf’s Law), as well as less common cases like bullets during deadly conflicts, recognition in social networks, heat between the atmosphere and sea-ice floes, and, finally, mass of water vapors between pores in solids. This last case is examined closely in the present article based on extensive experimental data. It is shown that the transferred mass between pores, which eventually grow towards a power law distribution, may be expressed using different parameters, either transferred surface area, or transferred volume, or transferred pore length or transferred pore anisotropy. These distinctions lead to different power laws of variable strength as reflected by the corresponding exponent. The exponents depend quantitatively on the spread of frequency distribution of the examined parameter and tend to zero as the spread of distribution tends to a single order of magnitude. A comparison between the energy and the entropy of different kinds of pore distributions reveals that these two statistical parameters are linearly related, implying that the system poise at a critical state and the exchangeable quantities are the most convenient operations helping to keep this balance. Full article
(This article belongs to the Section Chemical Sciences)
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14 pages, 1059 KiB  
Article
Triple Attention Mechanism with YOLOv5s for Fish Detection
by Wei Long, Yawen Wang, Lingxi Hu, Jintao Zhang, Chen Zhang, Linhua Jiang and Lihong Xu
Fishes 2024, 9(5), 151; https://doi.org/10.3390/fishes9050151 (registering DOI) - 23 Apr 2024
Abstract
Traditional fish farming methods suffer from backward production, low efficiency, low yield, and environmental pollution. As a result of thorough research using deep learning technology, the industrial aquaculture model has experienced gradual maturation. A variety of complex factors makes it difficult to extract [...] Read more.
Traditional fish farming methods suffer from backward production, low efficiency, low yield, and environmental pollution. As a result of thorough research using deep learning technology, the industrial aquaculture model has experienced gradual maturation. A variety of complex factors makes it difficult to extract effective features, which results in less-than-good model performance. This paper proposes a fish detection method that combines a triple attention mechanism with a You Only Look Once (TAM-YOLO)model. In order to enhance the speed of model training, the process of data encapsulation incorporates positive sample matching. An exponential moving average (EMA) is incorporated into the training process to make the model more robust, and coordinate attention (CA) and a convolutional block attention module are integrated into the YOLOv5s backbone to enhance the feature extraction of channels and spatial locations. The extracted feature maps are input to the PANet path aggregation network, and the underlying information is stacked with the feature maps. The method improves the detection accuracy of underwater blurred and distorted fish images. Experimental results show that the proposed TAM-YOLO model outperforms YOLOv3, YOLOv4, YOLOv5s, YOLOv5m, and SSD, with a mAP value of 95.88%, thus providing a new strategy for fish detection. Full article
23 pages, 959 KiB  
Systematic Review
Enhancing Chronic Non-Cancer Pain Management: A Systematic Review of Mindfulness Therapies and Guided Imagery Interventions
by Beatriz Manarte Pinto, Isaura Tavares and Daniel Humberto Pozza
Medicina 2024, 60(5), 686; https://doi.org/10.3390/medicina60050686 (registering DOI) - 23 Apr 2024
Abstract
Background and Objectives: There has been an increasing interest in the use of non-pharmacological approaches for the multidimensional treatment of chronic pain. The aim of this systematic review was to assess the effectiveness of mindfulness-based therapies and Guided Imagery (GI) interventions in [...] Read more.
Background and Objectives: There has been an increasing interest in the use of non-pharmacological approaches for the multidimensional treatment of chronic pain. The aim of this systematic review was to assess the effectiveness of mindfulness-based therapies and Guided Imagery (GI) interventions in managing chronic non-cancer pain and related outcomes. Materials and Methods: Searching three electronic databases (Web of Science, PubMed, and Scopus) and following the PRISMA guidelines, a systematic review was performed on Randomized Controlled Trials (RCTs) and pilot RCTs investigating mindfulness or GI interventions in adult patients with chronic non-cancer pain. The Cochrane Risk of Bias Tool was utilized to assess the quality of the evidence, with outcomes encompassing pain intensity, opioid consumption, and non-sensorial dimensions of pain. Results: Twenty-six trials met the inclusion criteria, with most of them exhibiting a moderate to high risk of bias. A wide diversity of chronic pain types were under analysis. Amongst the mindfulness interventions, and besides the classical programs, Mindfulness-Oriented Recovery Enhancement (MORE) emerges as an approach that improves interoception. Six trials demonstrated that mindfulness techniques resulted in a significant reduction in pain intensity, and three trials also reported significant outcomes with GI. Evidence supports a significant improvement in non-sensory dimensions of pain in ten trials using mindfulness and in two trials involving GI. Significant effects on opioid consumption were reported in four mindfulness-based trials, whereas one study involving GI found a small effect with that variable. Conclusions: This study supports the evidence of benefits of both mindfulness techniques and GI interventions in the management of chronic non-cancer pain. Regarding the various mindfulness interventions, a specific emphasis on the positive results of MORE should be highlighted. Future studies should focus on specific pain types, explore different durations of the mindfulness and GI interventions, and evaluate emotion-related outcomes. Full article
(This article belongs to the Section Psychiatry)
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32 pages, 22322 KiB  
Article
Enhanced Energy Absorption with Bioinspired Composite Triply Periodic Minimal Surface Gyroid Lattices Fabricated via Fused Filament Fabrication (FFF)
by Dawit Bogale Alemayehu and Masahiro Todoh
J. Manuf. Mater. Process. 2024, 8(3), 86; https://doi.org/10.3390/jmmp8030086 (registering DOI) - 23 Apr 2024
Abstract
Bio-inspired gyroid triply periodic minimum surface (TPMS) lattice structures have been the focus of research in automotive engineering because they can absorb a lot of energy and have wider plateau ranges. The main challenge is determining the optimal energy absorption capacity and accurately [...] Read more.
Bio-inspired gyroid triply periodic minimum surface (TPMS) lattice structures have been the focus of research in automotive engineering because they can absorb a lot of energy and have wider plateau ranges. The main challenge is determining the optimal energy absorption capacity and accurately capturing plastic plateau areas using finite element analysis (FEA). Using nTop’s Boolean subtraction method, this study combined walled TPMS gyroid structures with a normal TPMS gyroid lattice. This made a composite TPMS gyroid lattice (CTG) with relative densities ranging from 14% to 54%. Using ideaMaker 4.2.3 (3DRaise Pro 2) software and the fused deposition modeling (FDM) Raise3D Pro 2 3D printer to print polylactic acid (PLA) bioplastics in 1.75 mm filament made it possible to slice computer-aided design (CAD) models and fabricate 36 lattice samples precisely using a layer-by-layer technique. Shimadzu 100 kN testing equipment was utilized for the mechanical compression experiments. The finite element approach validates the results of mechanical compression testing. Further, a composite CTG was examined using a field emission scanning electron microscope (FE-SEM) before and after compression testing. The composite TPMS gyroid lattice showed potential as shock absorbers for vehicles with relative densities of 33%, 38%, and 54%. The Gibson–Ashby model showed that the composite TPMS gyroid lattice deformed mainly by bending, and the size effect was seen when the relative densities were less than 15%. The lattice’s relative density had a significant impact on its ability to absorb energy. The research also explored the use of these innovative foam-like composite TPMS gyroid lattices in high-speed crash box scenarios to potentially enhance vehicle safety and performance. The structures have tremendous potential to improve vehicle safety by acting as advanced shock absorbers, which are particularly effective at higher relative densities. Full article
(This article belongs to the Special Issue Lattice Structure and Metamaterial Design for Additive Manufacturing)
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