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Forecasting the Change of Renal Stone Occurrence Rates in AstronautsChanges in urine chemistry, during and post flight, potentially increases the risk of renal stones in astronauts. Although much is known about the effects of space flight on urine chemistry, no inflight incidences of renal stones in US astronauts exists and the question How much does this risk change with space flight? remains difficult to accurately quantify. In this discussion, we tackle this question utilizing a combination of deterministic and probabilistic modeling that implements the physics behind free stone growth and agglomeration, speciation of urine chemistry and published observations of population renal stone incidences to estimate changes in the rate of renal stone occurrence.
Document ID
20170004121
Acquisition Source
Glenn Research Center
Document Type
Presentation
Authors
Myers, J. (NASA Glenn Research Center Cleveland, OH United States)
Goodenow, D. (NASA Glenn Research Center Cleveland, OH United States)
Gokoglu, S. (NASA Glenn Research Center Cleveland, OH United States)
Kassemi, M. (Case Western Reserve Univ. Cleveland, OH, United States)
Date Acquired
May 1, 2017
Publication Date
October 26, 2016
Subject Category
Aerospace Medicine
Report/Patent Number
GRC-E-DAA-TN36642
Meeting Information
Meeting: Annual Meeting of the American Society for Gravitational and Space Research (ASGSR) 2016
Location: Cleveland, OH
Country: United States
Start Date: October 26, 2016
End Date: October 29, 2016
Sponsors: American Society for Gravitational and Space Research
Funding Number(s)
WBS: WBS 444543.01.02.10
CONTRACT_GRANT: NNC13BA10B
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
physiological response
biomechanics
gravitational physiology

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