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Symbiosis and the origin of eukaryotic motilityOngoing work to test the hypothesis of the origin of eukaryotic cell organelles by microbial symbioses is discussed. Because of the widespread acceptance of the serial endosymbiotic theory (SET) of the origin of plastids and mitochondria, the idea of the symbiotic origin of the centrioles and axonemes for spirochete bacteria motility symbiosis was tested. Intracellular microtubular systems are purported to derive from symbiotic associations between ancestral eukaryotic cells and motile bacteria. Four lines of approach to this problem are being pursued: (1) cloning the gene of a tubulin-like protein discovered in Spirocheata bajacaliforniesis; (2) seeking axoneme proteins in spirochets by antibody cross-reaction; (3) attempting to cultivate larger, free-living spirochetes; and (4) studying in detail spirochetes (e.g., Cristispira) symbiotic with marine animals. Other aspects of the investigation are presented.
Document ID
19920004421
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Margulis, L.
(Massachusetts Univ. Amherst, MA, United States)
Hinkle, G.
(Massachusetts Univ. Amherst, MA, United States)
Date Acquired
September 6, 2013
Publication Date
October 1, 1991
Publication Information
Publication: NASA, Washington, Fourth Symposium on Chemical Evolution and the Origin and Evolution of Life
Subject Category
Space Biology
Accession Number
92N13639
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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