Cannabis is useful for treating many ailments, but has unwanted side effects. Drugs that control signalling by cannabinoids found naturally in the body might be more useful.
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References
House of Lords Select Committee on Science and Technology Cannabis: The Scientific and Medical Evidence (The Stationery Office, London, 1998).
National Institutes of Health Report on the Medical Uses of Marijuana http://www.nih.gov/news/medmarijuana/MedicalMarijuana.htm (1997).
Piomelli, D., Giuffrida, A., Calignano, A. & Fonseca, R. Trends Pharmacol. Sci. 21, 218–224 (2000).
Wilson, R. I. & Nicoll, R. A. Nature 410, 588–592 (2001).
Ohno-Shosaku, T., Maejima, T. & Kano, M. Neuron 29, 729–738 (2001).
Kreitzer, A. C. & Regehr, W. G. Neuron 29, 717–727 (2001).
Pilter, T. A. & Alger, B. E. J. Neurosci. 12, 4122–4132 (1992).
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Christie, M., Vaughan, C. Cannabinoids act backwards. Nature 410, 527–530 (2001). https://doi.org/10.1038/35069167
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DOI: https://doi.org/10.1038/35069167
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