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Presence of Imidazoleacetic Acid Riboside and Ribotide in Rat Tissues

Nature volume 203, pages 1178–1179 (1964)Cite this article

Abstract

THE products of histamine metabolism in vivo have been catalogued in investigations of the urine1,2, but relatively little work has been done on metabolites present in tissues. Since excreted metabolites reflect only the composite outflow of terminal products and need not represent the metabolites present in a tissue, it seemed of interest to examine the radioactive compounds present in some tissues after the injection of labelled histamine and histidine. A special effort was made to demonstrate the presence of histamine adenine dinucleotide (HAD) and histamine adenine dinucleotide phosphate (HADP)3,4.

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Authors and Affiliations

  1. Department of Pharmacology, Yale University School of Medicine, New Haven, Conn.

    J. D. ROBINSON & J. P. GREEN

Authors
  1. J. D. ROBINSON
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  2. J. P. GREEN
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ROBINSON, J., GREEN, J. Presence of Imidazoleacetic Acid Riboside and Ribotide in Rat Tissues. Nature 203, 1178–1179 (1964). https://doi.org/10.1038/2031178a0

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