Abstract
PLASTIC material inserted under the skin of mice and certain other laboratory animals frequently leads to the formation of sarcomatous transplantable tumours1,2. This finding deserves consideration in view of the use of plastics in human surgery. It also attracts theoretical interest as an example of “physical” carcinogenesis. (The role of chemical cofactors is still under dispute although evidence is mounting against it3.)
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BRAND, K., BUOEN, L. & BBAND, I. Premalignant Cells in Tumorigenesis induced by Plastic Film. Nature 213, 810 (1967). https://doi.org/10.1038/213810a0
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DOI: https://doi.org/10.1038/213810a0
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