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Metabolic Behaviour of Isozymes of Acetylcholinesterase

Abstract

CHOLINESTERASE (ChE) from various sources can be separated into different molecular forms or isozymes1 and we have resolved several bands with ChE activity in extracts of rat neural tissue using disc electrophoresis (Fig. 1). To gain more information about these isozymes, we have studied their physiological properties, particularly their turnover, and have detected an isozyme which seems to have a rapid rate of turnover.

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DAVIS, G., AGRANOFF, B. Metabolic Behaviour of Isozymes of Acetylcholinesterase. Nature 220, 277–280 (1968). https://doi.org/10.1038/220277a0

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