Abstract
THE cells of human and murine leukaemias are usually either diploid or very close to diploidy, even when their karyotypes show some specific morphological abnormalities. In a study of spontaneous and transplanted AKR leukaemias, Wakonig-Vaartaja and Stich1 found that most of the mitoses had a normal diploid set of forty chromosomes although there were forty-one chromosomes in one-third of the cases. Identical observations have been reported by Kurita and Yosida2.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Wakonig-Vaartaja, R., and Stich, H. F., J. Nat. Cancer Inst., 25, 295 (1960).
Kurita, Y., and Yosida, T. H., Gann, 52, 257 (1961).
Leonard, A., and Deknudt, G. H., Nature, 214, 504 (1967).
Koller, P. C., Europ. J. Cancer, 3, 279 (1967).
Ford, C. E., in Tissue Grafting and Radiation (Academic Press, New York, 1966).
Duplan, J. F., Nouv. Revue Fr. Hémat., 2, 551 (1962).
Lejeune, J., and Berger, R., CR Acad. Sci., Paris, 263, 1880 (1966).
Lejeune, J., Berger, R., Haines, M., Lafourcade, J., Vialatte, J., Satge, P., and Turpin, R., CR Acad. Sci., Paris, 256, 1195 (1963).
De Grouchy, J., and Wolff, E., Europ. J. Cancer, 5, 159 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LEGRAND, E., DUPLAN, J. Presence of an Additional Metacentric Chromosome in AKR/TIALD Leukaemic Cells. Nature 225, 737–738 (1970). https://doi.org/10.1038/225737a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/225737a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.