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The Intercistronic Divide: Translation of an Intercistronic Region in the Histidine Operon of Salmonella typhimurium

Nature volume 226, pages 908–911 (1970)Cite this article

Abstract

A frameshift mutation near the end of the hisD gene of the histidine operon results in the production of an active hisD gene product. Analysis of the C-terminal sequence of the mutant protein establishes that the normal in vivo hisD chain termination codon can be UAA or UGA but not UAG, and demonstrates the existence of an Intercistronic region between two genes of the operon.

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Authors and Affiliations

  1. Laboratory of Molecular Biology, National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland, 20014

    MATTHEW M. RECHLER & ROBERT G. MARTIN

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  1. MATTHEW M. RECHLER
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  2. ROBERT G. MARTIN
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RECHLER, M., MARTIN, R. The Intercistronic Divide: Translation of an Intercistronic Region in the Histidine Operon of Salmonella typhimurium. Nature 226, 908–911 (1970). https://doi.org/10.1038/226908a0

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