Abstract
A NUMBER of excitable membranes exhibit a long-lasting depression of the delayed outward current during a depolarising pulse. One explanation is that there is a true inactivation of potassium gates1–3, and another is that it is due to an accumulation of potassium ions in a limited volume extracellular space, reducing the electric driving force for potassium ions3,4. We have examined the relationship between the depression of net outward current and concomitant changes in potassium ion activity recorded with a potassium-sensitive microelectrode positioned close to the surface of monopolar ganglion cells of the snail Helix pomatia.
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References
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LUX, H., ECKERT, R. Inferred slow inward current in snail neurones. Nature 250, 574–576 (1974). https://doi.org/10.1038/250574a0
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DOI: https://doi.org/10.1038/250574a0
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