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Novel cell cycle control of RNA synthesis in yeast

Abstract

During the fission yeast cell cycle, the rate of polyadenylated messenger RNA synthesis doubles when the cell reaches a critical size. This size-related control maintains average mRNA content in balance with total cell mass during exponential growth, even in cells growing at different absolute growth rates per cell.

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Fraser, R., Nurse, P. Novel cell cycle control of RNA synthesis in yeast. Nature 271, 726–730 (1978). https://doi.org/10.1038/271726a0

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