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A plasmid DNA primase active in discontinuous bacterial DNA replication

Nature volume 290, pages 217–221 (1981)Cite this article

Abstract

A DNA primase encoded by an IncIα plasmid promotes efficient DNA replication in a primase-defective mutant of Escherichia coli. This finding implies that the plasmid enzyme can prime discontinuous DNA synthesis of the bacterial chromosome. The plasmid gene encodes two large, antigenically related proteins which differ from E. coli primase.

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Author information

Authors and Affiliations

  1. Department of Genetics, University of Leicester, Leicester, LE1 7RH, UK

    Brian M. Wilkins & Graham J. Boulnois

  2. Max-Planck-Institut für Molekulare Genetik, Abteilung Schuster, Berlin-Dahlem, FRG

    Erich Lanka

Authors
  1. Brian M. Wilkins
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  2. Graham J. Boulnois
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  3. Erich Lanka
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Wilkins, B., Boulnois, G. & Lanka, E. A plasmid DNA primase active in discontinuous bacterial DNA replication. Nature 290, 217–221 (1981). https://doi.org/10.1038/290217a0

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  • DOI: https://doi.org/10.1038/290217a0

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