Abstract
Scott Blair, Cowie and Coppen1 found that when uterine cervical secretions from the cow were examined in an emptying capillary viscometer the shape of the flow curve changed during pregnancy; but Scott Blair, Cowie and Folley2 showed that a parameter derived from such curves gave a reliable test for pregnancy only about sixteen weeks after conception. It seemed likely that the test could be improved in four ways: (1) by ensuring that all samples were taken directly from the cervix without vaginal contamination; (2) by using unmixed samples, thereby avoiding disturbance to the structure; (3) by measuring changes in pressure at constant rate of flow rather than extruding at constant pressure and measuring rates, thus largely eliminating accelerations; and (4) by averaging the results of two or three tests.
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References
Scott Blair, G. W., Cowie, A. T., and Coppen, F. M. V., Nature, 149, 609 (1942).
Scott Blair, G. W., Cowie, A. T., and Folley, S. J., J. Physiol., 101, 11 P (1942).
Clift, A. F., Glover, F. A., and Scott Blair, G. W., Lancet, 258, 1154 (1950).
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GLOVER, F., BLAIR, G. Bovine Sterility and Pregnancy in Relation to the Rheological Properties of Cervical Secretions. Nature 167, 285 (1951). https://doi.org/10.1038/167285a0
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DOI: https://doi.org/10.1038/167285a0
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