Abstract
Krebs and Eggleston1 have isolated ketoglutaric acid (I) during a study of arsenite-inhibited pyruvate utilization by pigeon's breast muscle. Lockwood and Stodola2 have isolated substantial yields of the same compound from a Pseudomonas fluorescens fermentation of glucose. From moulds its isolation has been reported only by Uemura3, who obtained it on deamination of glutamic acid by Aspergillus oryzœ.
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Krebs, H. A., and Eggleston, L. V., Biochem. J., 34, 1383 (1940).
Lockwood, L. B., and Stodola, F. H., J. Biol. Chem., 164, 81 (1946).
Uemura, T., J. Agric. Chem. Soc. Japan, 15, 353 (1939), from Chem. Abs., 33, 8872 (1939).
Foster, J. W., U.S.P. 2,458,495 (Jan. 11, 1949).
Cavallini, D., Frontali, N., and Toschi, G., Nature, 163, 568 (1949).
Datta, S. P., Harris, H., and Rees, K. R., Biochem. J., 46, xxxvi (Proc. Biochem. Soc.) (1950).
Walker, T. K., Hall, A. N., and Hopton, J. W. (see preceding communication).
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HOCKENHULL, D., WILKIN, G. & WINDER, F. Production of Ketoglutarate by Penicillium chrysogenum. Nature 168, 1043 (1951). https://doi.org/10.1038/1681043a0
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DOI: https://doi.org/10.1038/1681043a0
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