Abstract
THE first clearly proved case of total sex-linkage in the house mouse has been found – a fact worthy of record since very few sex-linked genes are yet known in mammals other than man, and none in the rodents. Apart from man, where hæmophilia and colour-blindness are the best known of a number of more or less certainly sex-linked genes1, there are only yellow in cats2 and hæmophilia in dogs3. In the mouse two genes, mottled and brindled, have been described4 which may be totally sex-linked; but this cannot be directly proved as both genes are lethal in males. A test using females heterozygous for the new gene and for mottled or brindled should settle this point.
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FALCONER, D. A Totally Sex-linked Gene in the House Mouse. Nature 169, 664–665 (1952). https://doi.org/10.1038/169664b0
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DOI: https://doi.org/10.1038/169664b0
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