Abstract
THE brief reference in Nature of December 13, p. 1002, to a paper by James and Thewlis1 on the separation and identification of solanaceous alkaloids in normal and grafted plants of Atropa belladonna and Datura innoxia prompts us to place on record certain results we have obtained in a similar study. So far as we are aware, the alkaloids of D. innoxia have not hitherto been fully characterized2. James and Thewlis state that they found hyoscine and hyoscyamine to be present and, from evidence of the hyoscine : hyoscyamine ratios in the two plants and in their reciprocal grafts, have deduced that alkaloid synthesis occurs mainly in the roots.
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References
James and Thewlis, New Phytol., 51, 250 (1952).
Haller, Thesis No. 1081, Geneva (1946). Gerlach, Econ. Bot., 2, 436 (1948). Hester and Davy, J. Amer. Pharm. Assoc., 22, 514 (1933).
Timmerman, Pharm. J., 118, 571 (1928).
Evans and Partridge, Quart. J. Pharm., 21, 126 (1948); J. Pharm., Lond., 1, 593 (1949); 4, 769 (1952).
Evans and Partridge, J. Pharm., Lond. (in the press).
Evans and Partridge, Nature, 169, 333 (1952).
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EVANS, W., PARTRIDGE, M. Alkaloids of Datura innoxia. Nature 171, 656 (1953). https://doi.org/10.1038/171656b0
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DOI: https://doi.org/10.1038/171656b0
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