Abstract
MEASLES virus antigen has been specifically identified in the nuclei of infected cells by means of the fluorescent antibody technique; and the development and spread of virus antigen in amnion and other human cells have been correlated with observations made in a concurrent study of fine structure1. During a continuation of the latter investigation we have found that crystallites made up of ordered arrays of electron-dense particles occur within nuclei of infected human amnion cells, and have also observed extracellular particles that can be interpreted as mature virus.
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References
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BAKER, R., GORDON, I. & RAPP, F. Electron-dense Crystallites in Nuclei of Human Amnion Cells infected with Measles Virus. Nature 185, 790–791 (1960). https://doi.org/10.1038/185790a0
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DOI: https://doi.org/10.1038/185790a0
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