Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effects of Administration of Oxytocin and Prolactin on Nucleic Acids and Phosphoprotein Contents of Mammary Glands in Lactating Rats

Abstract

Benson and Folley1 have demonstrated from the histological point of view that the injection of oxytocin as well as prolactin into lactating rats after removal of their litters showed a marked retarding effect on the involution of mammary gland tissue, and this finding was confirmed by us2 and others3,4. In previous experiments2,5, however, we failed to see the effects on the in vitro respiratory activity of the mammary gland tissue.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Benson, G. K., and Folley, S. J., Nature, 177, 700 (1956); J. Endocrinol., 16, 189 (1957).

    Article  ADS  CAS  Google Scholar 

  2. Yokoyama, A., and Ôta, K., Endocrinol. Japon., 6, 259 (1959).

    Article  CAS  Google Scholar 

  3. McCann, S. M., Mack, R., and Gale, C., Endocrinol., 64, 870 (1959).

    Article  CAS  Google Scholar 

  4. Meites, J., J. Animal Sci., 17, 1223 (1958); Fed. Proc., 18, 103 (1959).

    Google Scholar 

  5. Ôta, K., and Yokoyama, A., Nature, 182, 1509 (1958).

    Article  ADS  Google Scholar 

  6. Greenbaum, A. L., and Slater, T. F., Biochem. J., 66, 155 (1957).

    Article  CAS  Google Scholar 

  7. Griffith, D. R., and Turner, C. W., Proc. Soc. Exp. Biol. and Med., 95, 347 (1957); 107, 668 (1961).

    Article  CAS  Google Scholar 

  8. Kirkham, W. R., and Turner, C. W., Proc. Soc. Exp. Biol. and Med., 83, 123 (1953).

    Article  CAS  Google Scholar 

  9. Kuretani, K., Rep. Sci. Res. Inst. (Tokyo), 33, 80 (1957).

    CAS  Google Scholar 

  10. Schneider, W. C., J. Biol. Chem., 164, 747 (1946).

    CAS  PubMed  Google Scholar 

  11. Delory, G. E., Biochem. J., 32, 1161 (1938).

    CAS  Google Scholar 

  12. Nakamura, M., J. Agric. Chem. Soc. Japan, 24, 1 (1950).

    CAS  Google Scholar 

  13. Allen, R. J. L., Biochem. J., 34, 858 (1940).

    Article  CAS  Google Scholar 

  14. Hooker, C. W., and Williams, W. L., Endocrinol., 28, 42 (1941).

    Article  CAS  Google Scholar 

  15. Johnson, R. M., and Alfredson, B. V., Fed. Proc., 17, 81 (1958).

    Google Scholar 

  16. Williams, W. L., Anat. Rec., 93, 171 (1945).

    Article  CAS  Google Scholar 

  17. Meites, J., and Hopkins, T. F., J. Endocrinol., 22, 207 (1961).

    Article  CAS  Google Scholar 

  18. Meites, J., and Nicoll, C. S., Endocrinol., 65, 572 (1959).

    Article  CAS  Google Scholar 

  19. Meites, J., Nicoll, C. S., and Talwalker, R. K., Proc. Soc. Exp. Biol. and Med., 103, 119 (1960).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ÔTA, K., YOKOYAMA, A. & SHINDE, Y. Effects of Administration of Oxytocin and Prolactin on Nucleic Acids and Phosphoprotein Contents of Mammary Glands in Lactating Rats. Nature 195, 77–78 (1962). https://doi.org/10.1038/195077b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/195077b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing