Abstract
SEVERAL authors1–3 have shown that the minor anodic fraction of hæmoglobin obtained by electrophoresis at pH 8.6 is part of the hæmoglobin modified during the ageing of the red cells. Proof is submitted here that the modification of the electrical charge of hæmoglobin A3 () is due only to the modification of the β-chain. This is proved by comparison of the electrophoretic migration of the hybrids obtained between canine hæmoglobin HbCAN and HbA and between HbCAN and .
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ROSA, J., LABIE, D. Change in A3 Hæmoglobin due to β-Chain. Nature 196, 901 (1962). https://doi.org/10.1038/196901a0
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DOI: https://doi.org/10.1038/196901a0
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