Abstract
TESTOSTERONE and similar androgens promote the anabolism of proteins. Retention of nitrogen was observed after administration of androgens to gonadectomized animals1,2. Male sex hormones also act directly on the skeleton. They enhance endochondrial ossification3 and increase metaphyseal growth4. They also increase the fusion of osteocartilagenous and bone grafts in rats and accelerate osteogenic reactions in the surrounding tissues5.
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SAID, A., SOLIMAN, F., ABDO, M. et al. Variations in the Levels of Androgens and Gonadotrophic Hormones in the Blood of Rats during Healing of Fractures. Nature 198, 294 (1963). https://doi.org/10.1038/198294a0
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DOI: https://doi.org/10.1038/198294a0
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