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Dehydroxylation of Caffeic Acid by Rat and Rabbit Cæcal Contents and Sheep Rumen Liquor

Nature volume 198, pages 684–685 (1963)Cite this article

Abstract

THE dehydroxylation of 3,4-dihydroxyphenylacetic acid (homoprotocatechuic acid) to m-hydroxyphenylacetic acid in the animal body was first reported by Booth et al.1, and was confirmed by Scheline et al.2, with 3,4-dihydroxyphenylacetic acid labelled with carbon-14. A claim has been made recently3 that noradrenaline is converted to m-hydroxyphenylacetic acid in guinea pigs; such a conversion involves not only dehydroxylation in the aromatic nucleus but also in the aliphatic side-chain of noradrenaline.

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References

  1. Booth, A. N., Murray, C. W., Jones, F. T., and DeEds, F., J. Biol. Chem., 223, 251 (1956).

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  2. Scheline, R. R., Williams, R. T., and Wit, J. G., Nature, 188, 849 (1960).

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  3. Smith, A. A., Biochim. Biophys. Acta, 69, 203 (1963).

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Author notes

  1. A. N. BOOTH: On leave of absence from the Western Regional Research Laboratory (U.S. Department of Agriculture), Albany, California.

Authors and Affiliations

  1. Department of Biochemistry, St. Mary's Hospital Medical School, London, W.2

    A. N. BOOTH & R. T. WILLIAMS

Authors
  1. A. N. BOOTH
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  2. R. T. WILLIAMS
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BOOTH, A., WILLIAMS, R. Dehydroxylation of Caffeic Acid by Rat and Rabbit Cæcal Contents and Sheep Rumen Liquor. Nature 198, 684–685 (1963). https://doi.org/10.1038/198684a0

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