A new study sheds light on the mechanism regulating the translation of localized mRNAs at their destination. Phosphorylation of an RNA-binding protein by Src promotes complex disassembly and allows translation of the localized transcript.
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Acknowledgements
We thank L. DesGroseillers and W. Sossin for sharing unpublished data and E. Querido for critical reading of the manuscript.
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Paquin, N., Chartrand, P. Knowing when to let go. Nat Struct Mol Biol 12, 1026–1027 (2005). https://doi.org/10.1038/nsmb1205-1026
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DOI: https://doi.org/10.1038/nsmb1205-1026