A recent study using electron microscopy provides a detailed view of the oligomerization of a protein complex on the surface of a microtubule polymer. The findings point to a new type of interaction that may be well suited to couple the movement of cargo to dynamic cytoskeletal polymers.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Westermann, S., Drubin, D.G. & Barnes, G. Annu. Rev. Biochem. 76, 563–591 (2007).
Wang, H.W. et al. Nat. Struct. Mol. Biol. 14, 721–726 (2007).
Miranda, J.J., De Wulf, P., Sorger, P.K. & Harrison, S.C. Nat. Struct. Mol. Biol. 12, 138–143 (2005).
Asbury, C.L., Gestaut, D.R., Powers, A.F., Franck, A.D. & Davis, T.N. Proc. Natl. Acad. Sci. USA 103, 9873–9878 (2006).
Franck, A.D. et al. Nat. Cell Biol. 9, 832–837 (2007).
Westermann, S. et al. Mol. Cell 17, 277–290 (2005).
Westermann, S. et al. Nature 440, 565–569 (2006).
Miranda, J.J., King, D.S. & Harrison, S.C. Mol. Biol. Cell 18, 2503–2510 (2007).
Joglekar, A.P., Bouck, D.C., Molk, J.N., Bloom, K.S. & Salmon, E.D. Nat. Cell Biol. 8, 581–585 (2006).
Cheeseman, I.M. et al. Cell 111, 163–172 (2002).
Desai, A. & Mitchison, T.J. Annu. Rev. Cell Dev. Biol. 13, 83–117 (1997).
Grishchuk, E.L., Molodtsov, M.I., Ataullakhanov, F.I. & McIntosh, J.R. Nature 438, 384–388 (2005).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Sandall, S., Desai, A. When it comes to couple(r)s, do opposites attract?. Nat Struct Mol Biol 14, 790–792 (2007). https://doi.org/10.1038/nsmb0907-790
Issue Date:
DOI: https://doi.org/10.1038/nsmb0907-790