Biochimica et Biophysica Acta (BBA) - General Subjects
Induction of tryptophan oxygenase and tyrosine aminotransferase by metabolites of hydrocortisone
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Role of the kynurenine pathway and the endocannabinoid system as modulators of inflammation and personality traits
2019, PsychoneuroendocrinologyCitation Excerpt :For example, pharmacological blockade or genetic deletion of cannabinoid CB1 receptor increases stress-induced hypothalamic-pituitary-adrenal axis (HPA axis) activation and secretion of glucocorticoids (Patel et al., 2004; Steiner et al., 2008; Urigüen et al., 2004). Glucocorticoids activate TDO in mice (Knox, 1951; Voigt and Sekeris, 1980), which (like IDO1) is the first enzyme of the kynurenine pathway, potentially stimulating the production of the downstream metabolite PIC. Thus, it is possible that the decrease in 2-AG would raise the levels of PIC through increased stimulation of the kynurenine pathway by glucocorticoids in our patient cohort, however it is unknown if HPA axis-mediated activation of the kynurenine pathway occurs in humans.
Glucocorticoid-recognizing and -effector sites in rat liver plasma membrane. Kinetics of corticosterone uptake by isolated membrane vesicles. III. Specificity and stereospecificity
1998, Journal of Steroid Biochemistry and Molecular BiologyGlucocorticoid-recognizing and -effector sites in rat liver plasma membrane. Kinetics of corticosterone uptake by isolated membrane vesicles-II. Comparative influx and efflux
1992, Journal of Steroid Biochemistry and Molecular BiologyMetyrapone modulation of tyrosine aminotransferase induction by dexamethasone in cultured hepatocytes
1990, Biochemical and Biophysical Research CommunicationsGlucocorticoids and the isolated rat hepatocyte
1986, Biochemical and Biophysical Research CommunicationsImmunochemical studies on biosynthesis of rat plasma angiotensinogen and its regulation by cortisol
1985, BBA - General Subjects
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Present address: Institute for Organic Chemistry and Biochemistry, University of Hamburg, Martin-Luther-King-Platz 6, D-2000 Hamburg 13, F.R.G.
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Present address: National Hellinic Research Foundation, Biological Research Center, 48 Vassileos Constantinou Avenue, Athens 501/I, Greece.