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Neue acetonylsubstituierte Azole I. 5-Acetonyl-1,2,4-oxadiazole

New acetonylsubstituted azoles, I. 5-Acetonyl-1,2,4-oxadiazoles

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

Aliphatic amidoximesR—C (NH2)=NOH react with diketene to yield 5-acetonyl-3-alkyl-1,2,4-oxadiazoles, which are susceptible to a wide variety of reactions at the keto-group as well as at the methylene-group. Their transformations into 1-methyl-2-oxadiazolyl-vinylN,N-dimethylcarbamates, 2-chloro-1-oxadiazolylpropenes, 1-oxadiazolyl-2-(1,2,4-triazol-1-yl)propenes, 1,1-dichloro-1-oxadiazolylacetones and 3-hydroxy-2-oxadiazolyl-crotonic amides are described as well as their reactions with diazonium salts, with sodium nitrite and with carbon disulfide. Further products obtained are carbamates of of 1-oxadiazolyl-2-oxo-propane-1-oximes, 2-chloro-2-oxadiazolylvinyl phosphates and an oxadiazolyl pyrimidine.

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Authors and Affiliations

  1. Hoechst AG, D-6230, Frankfurt am Main 80, Bundesrepublik Deutschland

    Börries Kübel

Authors
  1. Börries Kübel
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Herrn Prof. Dr.Klaus Weissermel zu seinem 60. Geburtstag.

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Kübel, B. Neue acetonylsubstituierte Azole I. 5-Acetonyl-1,2,4-oxadiazole. Monatsh Chem 113, 781–792 (1982). https://doi.org/10.1007/BF00809019

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  • DOI: https://doi.org/10.1007/BF00809019

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