Skip to main content
Log in

A stochstic model for a two-compartment reversible system

  • Published:
Bulletin of Mathematical Biology Aims and scope Submit manuscript

Abstract

This paper discusses a general stochastic model for a two-compartment reversible system with non-homogeneous Poisson inputs, arbitrary residence times at each of the compartments and time-dependent transition probabilities. The probability distributions of the number of particles in each compartment and in the system are obtained together with the number of particles which depart from the system. In addition, various covariance functions with a time lag are obtained. Some of the above obtained results are deduced for time-independent arrivals, exponential residence times and time-independent transition probabilities. Fluctuations of the particles present in the system are also analysed. Similar analysis is provided for the model into which some particles are initially introduced at the system. Some possible applications are discussed at the end.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature

  • Cardenas, M. and J. H. Matis 1974. “On this Stochastic Theory of Compartments: Solution forn-Compartment Systems with Irreversible, Time-Dependent Transition Probabilities.”Bull. Math. Biol. 36, 489–504.

    Article  MATH  MathSciNet  Google Scholar 

  • — and —. 1975a. “On the Time-Dependent Reversible Stochastic Compartmental Model—I. The General Two-Compartment System.”Bull. Math. Biol. 37, 505–519.

    Article  MATH  MathSciNet  Google Scholar 

  • — and —. 1975b. “On the Time-Dependent Reversible Stochastic Compartmental Model-II. A Class ofn-Compartment Systems.”Bull. Math. Biol. 37, 555–564.

    Article  MATH  MathSciNet  Google Scholar 

  • El-Asfouri, S., A. S. Kapadia and B. C. McInnis. 1979. “Stochastic Compartmental Modelling and Parameter Estimation with Application to Cancer Treatment Follow-up Studies.”Bull. Math. Biol. 41, 203–215.

    Article  MATH  MathSciNet  Google Scholar 

  • Kapadia, A. S. and B. C. McInnis. 1976. “A Stochastic Compartmental Model with Continuous Infusion.”Bull. Math. Biol. 38, 695–700.

    MATH  MathSciNet  Google Scholar 

  • Marcus, A. H. 1978. “Abstract: Compartment Models as Semi-Markov Processes.”Biometrics 34, 740.

    Google Scholar 

  • Matis, J. H. 1972. “322 Note: Gemma Time Dependency in Blaxter's Compartmental Model.”Biometrics 28, 597–602.

    Article  Google Scholar 

  • Mehata, K. M. and D. D. Selvam. 1981. “A Stochastic Model for then-Compartment Irreversible System.”Bull. Math. Biol. 43, 549–561.

    MATH  MathSciNet  Google Scholar 

  • Parzen, E. 1964.Stochastic Processes. London: Holden-Day Inc.

    Google Scholar 

  • Purdue, P. 1974a. “Stochastic Theory of Compartments.”Bull. Math. Biol. 36, 305–309.

    Article  MATH  MathSciNet  Google Scholar 

  • — 1974b. “Stochastic Theory of Compartments: One and Two-Compartment Systems.”Bull. Math. Biol. 36, 577–587.

    Article  MATH  MathSciNet  Google Scholar 

  • — 1975. “Stochastic Theory of Compartments: An Open, Two-Compartment, Reversible System with Independent Poisson Arrivals.”Bull. Math. Biol. 37, 269–275.

    Article  MATH  MathSciNet  Google Scholar 

  • Sweet, A. L. and J. L. Bagdanoff 1969. “The Estimation of Parameters for a Commonly Used Stochastic Model.”AIChE J. 15, 100–105.

    Article  Google Scholar 

  • Thakur, A. K., A. Rescigno and D. E. Schafer. 1972. “On the Stochastic Theory of Compartments: I. A single Compartment Systems.”Bull. Math. Biophys. 34, 53–63.

    MATH  MathSciNet  Google Scholar 

  • —— and —. 1973. “On the Stochastic Theory of Compartments: II. Multi-Compartment System.”Bull. Math. Biol.,35, 263–271.

    Article  MATH  MathSciNet  Google Scholar 

  • Thakur, A. K. and A. Rescigno. 1978. “On the Stochastic Theory of Compartments: III General Time-Dependent Reversible Systems.”Bull. Math. Biol. 40, 237–246.

    Article  MATH  MathSciNet  Google Scholar 

  • Weiner, D. L. and P. Purdue. 1977. “The Stochastic Theory of Compartments—A Mamillary System.”Bull. Math. Biol.,39, 533–542.

    Article  MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mehata, K.M., Selvam, D.D. A stochstic model for a two-compartment reversible system. Bltn Mathcal Biology 44, 557–570 (1982). https://doi.org/10.1007/BF02459409

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02459409

Keywords

Navigation