Abstract
Schemes are presented for induced synthesis of the dissociable enzyme in which repeated use of the template is made. The role of the inducer is to release the repression. A mathematical analysis is carried out and expressions are obtained to describe the kinetics of enzyme formation. A practical case (penicillinase synthesis) is compared with theoretically derived equations by using an analogue computer to simulate an enzyme forming system. A good correlation between theoretical and experimental data is obtained.
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Heinmets, F., Herschman, A. Quantitative analysis of metabolic processes. II. A model-system for the synthesis of the dissociable enzyme and mathematical formulation of the process. Bulletin of Mathematical Biophysics 23, 277–295 (1961). https://doi.org/10.1007/BF02476741
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DOI: https://doi.org/10.1007/BF02476741