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Comparison of the protective ability of O and K immunity in mice after immunization withEscherichia coli

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Abstract

The protective abilities ofEscherichia coli O and K immunity against intraperitoneal infection was compared in CBA mice immunized with formalin-killed bacteria. The K13 immunity achieved seemed somewhat more effective than the O6 immunity. This was also reflected in a slightly more rapid clearance of a liveE. coli O6K13 bacteria in K13-immunized animals than in those immunized with O6. However, the protection achieved afterE. coli O6K2 and O2K1 immunization was related more to O immunity than to K immunity.

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Authors and Affiliations

  1. Institute of Medical Microbiology, Department of Clinical Bacteriology, University of Göteborg, Guldhedsgatan 10, S-413 46, Göteborg, Sweden

    Staffan Ahlsted & Bertil Kaijser

  2. Research and Development Laboratories, ASTRA Läkemedel AB, S-151 85, Södertälje, Sweden

    Eva Jerning

Authors
  1. Staffan Ahlsted
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  2. Eva Jerning
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  3. Bertil Kaijser
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Ahlsted, S., Jerning, E. & Kaijser, B. Comparison of the protective ability of O and K immunity in mice after immunization withEscherichia coli . Current Microbiology 6, 55–59 (1981). https://doi.org/10.1007/BF01566727

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