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Sexual compatibility between serotypes ofFilobasidiella neoformans (Cryptococcus neoformans)

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Abstract

Twenty-five of 37Cryptococcus neoformans strains of known serotype produced the basidiomycetousFilobasidiella state either alone or when paired with a strain of compatible mating-type. Sixteen strains were “α” mating-type, four strains were “a” mating-type, and five strains were self-fertile.F. neoformans serotypes A and D were interfertile with compatible mating-types ofF. bacillispora serotypes B and C.C. neoformans var.gattii was interfertile with compatible mating-types ofF. neoformans andF. bacillispora. F. bacillispora strains, which utilized creatinine andl-malic acid, were interfertile with compatible mating-types ofF. neoformans, which did not utilize creatinine andl-malic acid. The interfertility between serotypes and biotypes eliminates the need for recognizing the names ofC. neoformans var.gattii, C. bacillisporus, andF. bacillispora. It is proposed thatC. neoformans var.gattii andC. bacillisporus be regarded as later, facultative synonyms ofC. neoformans and thatF. bacillispora be regarded as a later, facultative synonym ofF. neoformans.

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Literature Cited

  1. Bennett, J. E., Kwon-Chung, K. J., Theodore, T. S. 1978. Biochemical differences between serotypes ofCryptococcus neoformans. Sabouraudia16:167–174.

    Google Scholar 

  2. Bowman, P. I., Ahearn, D. G. 1978. Ecology ofCryptococcus neoformans in Georgia, pp. 258–268. In: Proceedings of the IV international conference on the mycoses. PAHO Scientific Publication No. 356. Washington, D.C.: Pan American Health Organization.

    Google Scholar 

  3. Busse, O. 1894. Über parasitäre Zelleinschlüsse und ihre Züchtung. Centralblatt für Bakteriologie und Parasitenkunde16:175–180.

    Google Scholar 

  4. de Queiroz, L. A., Purchio, A. 1979.Filobasidiella neoformans obtido pelo cruzamento de amostras deCryptococcus neoformans serotipo D com AD. Revista de Microbiologia10:34–35.

    Google Scholar 

  5. Erke, K. H. 1976. Light microscopy of basidia, basidiospores, and nuclei in spores and hyphae ofFilobasidiella neoformans (Cryptococcus neoformans). Journal of Bacteriology128:445–455.

    Google Scholar 

  6. Evans, E. E. 1949. An immunologic comparison of twelve strains ofCryptococcus neoformans (Torula histolytica). Proceedings of the Society for Experimental Biology and Medicine71:644–646.

    Google Scholar 

  7. Evans, E. E. 1950. The antigenic composition ofCryptococcus neoformans. I. A serological classification by means of the capsular and agglutination reactions. Journal of Immunology64:423–430.

    Google Scholar 

  8. Evans, N. 1922.Torula infection. California State Journal of Medicine20:383–385.

    Google Scholar 

  9. Farhi, F., Blumer, G. S., Tacker, J. R. 1970.Cryptococcus neoformans. IV. The not-so-encapsulated yeast. Infection and Immunity1:526–531.

    Google Scholar 

  10. Freeman, W., Weidman, F. D. 1923. Cystic blastomycosis of the cerebral gray matter caused byTorula histolytica Stoddard and Cutler. Archives of Neurology and Psychiatry9:589–603.

    Google Scholar 

  11. Gatti, F., Eeckels, R. 1970. An atypical strain ofCryptococcus neoformans (San Felice) Vuillemin 1894. Part I. Description of the disease and of the strain. Annales de la Société Belge de Medicine Tropicale50:689–694.

    Google Scholar 

  12. Jong, S. C. 1980. Collection of fungi, pp. 218–465. In: Catalogue of strains I, 14th ed. Rockville, Maryland: American Type Culture Collection.

    Google Scholar 

  13. Kaufman, L., Blumer, S. 1968. Cryptococcosis: The awakening giant, pp. 176–182. In: Proceedings of the IV international conference on the mycoses. PAHO Scientific Publication No. 356. Washington, D. C.: Pan American Health Organization.

    Google Scholar 

  14. Kozel, T. R. 1977. Non-encapsulated variant ofCryptococcus neoformans. II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide. Infection and Immunity16:99–106.

    Google Scholar 

  15. Kwon-Chung, K. J. 1975. A new genus,Filobasidiella, the perfect state ofCryptococcus neoformans. Mycologia67:1197–1200.

    Google Scholar 

  16. Kwon-Chung, K. J. 1976. Morphogenesis ofFilobasidiella neoformans, the sexual state ofCryptococcus neoformans. Mycologia68:821–833.

    Google Scholar 

  17. Kwon-Chung, K. J. 1976. A new species ofFilobasidiella, the sexual state ofCryptococcus neoformans B and C serotypes. Mycologia68:942–946.

    Google Scholar 

  18. Kwon-Chung, K. J. 1978. Heterothallismvs. self-fertile isolates ofFilobasidiella neoformans (Cryptococcus neoformans), pp. 204–213. In: Proceedings of the IV international conference on the mycoses. PAHO Scientific Publication No. 356. Washington, D. C.: Pan American Health Organization.

    Google Scholar 

  19. Kwon-Chung, K. J., Bennett, J. E., Theodore, T. S. 1978.Cryptococcus bacillisporus sp. nov.: Serotype B-C ofCryptococcus neoformans. International Journal of Systematic Bacteriology28:616–620.

    Google Scholar 

  20. Lange, M. 1968. Genetical and cytological aspects of taxonomy, pp. 625–631. In: Ainsworth, G. C., Sussman, A. S. (eds.), The fungi, an advanced treatise, vol. III. New York: Academic Press.

    Google Scholar 

  21. Levin, E. A. 1937.Torula infection of the central nervous system. Archives of Internal Medicine59:667–684.

    Google Scholar 

  22. Lodder, J., Kreger-van Rij, N. J. W. 1952. Discussion of the genera belonging to the Cryptococcaceae, pp. 370–667. In: Lodder, J., Kreger-van Rij, N. J. W., (eds.), The yeasts, a taxonomic study. Amsterdam: North-Holland.

    Google Scholar 

  23. Sanfelice, F. 1894. Contributo alla morfologia e biologia dei blastomiceti che si sviluppana nei succhi di alcuni frutti. Roma University Institute Igiene Sperimentale Annales4:463–495.

    Google Scholar 

  24. Sheppe, W. M. 1924.Torula infection in man. American Journal of the Medical Sciences167:91–108.

    Google Scholar 

  25. Taylor, R. L., Duangmani, C. 1968. Occurrence ofCryptococcus neoformans in Thailand. American Journal of Epidemiology87:318–322.

    Google Scholar 

  26. Vanbreuseghem, R., Takashio, M. 1970. An atypical strain ofCryptococcus neoformans (San Felice) Vuillemin 1894. Part II.Cryptococcus neoformans var.gattii var. nov.. Annales de la Société Belge de Medicine Tropicale50:695–702.

    Google Scholar 

  27. van der Walt, J. P. 1965. The emendation of the genus,Kluyveromyces v. d. Walt. Antonie van Leeuwenhoek Journal of Microbiology and Serology31:341–348.

    Google Scholar 

  28. Wickerham, L. J. 1951. Taxonomy of yeasts, p. 11. U.S. Department of Agriculture Technical Bulletin 1029. Washington, D. C.: Government Printing Office.

    Google Scholar 

  29. Wickerham, L. J., Burton, K. A. 1962. Phylogeny and biochemistry of the genusHansenula. Bacteriological Reviews26:382–397.

    Google Scholar 

  30. Wilson, D. E., Bennett, J. E., Bailey, J. W. 1968. Serologic grouping ofCryptococcus neoformans. Proceedings of the Society for Experimental Biology and Medicine127:820–823.

    Google Scholar 

  31. Winge, O., Lausten, O. 1939. On 14 new yeast types produced by hybridization. Comptes Rendus des Travaux du Laboratoire Carlsberg Serie Physiologique22:337–356.

    Google Scholar 

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Authors and Affiliations

  1. Mycology Department, American Type Culture Collection, 12301 Parklawn Drive, 20852, Rockville, Maryland, USA

    Kathryn A. Schmeding & Shung C. Jong

  2. Department of Microbiology, George Washington University School of Medicine, 20052, Washington, D.C., USA

    Rudolph Hugh

Authors
  1. Kathryn A. Schmeding
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  2. Shung C. Jong
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  3. Rudolph Hugh
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Schmeding, K.A., Jong, S.C. & Hugh, R. Sexual compatibility between serotypes ofFilobasidiella neoformans (Cryptococcus neoformans) . Current Microbiology 5, 133–138 (1981). https://doi.org/10.1007/BF01578516

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