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Mechanical properties of diaphragm muscle in dogs

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Abstract

The mechanical properties of diaphragm muscle in dogs were measured. A portion of the diaphragm was isolated and formed into a pouch which in turn was connected to various hydraulic circuits. We measured pressure response to electrical stimulation for various voltages, frequencies and baseline pressures; and also contraction time. Further, we obtained pressure-volume curves and estimated the power output of the actively contracting muscle. From the results we conclude that the properties of the diaphragm muscle do not exclude its use as a myocardial substitute.

Sommaire

Nous avons mesuré les propriétés mécaniques du muscle du diaphragme du chien. Une portion du diaphragme fut isolée et façonnée en forme de poche avant d'être reliée à divers circuits hydrauliques. Nous avons mesuré la réponse à la pression créée par stimulation électrique à divers voltages, fréquences et pressions de base ainsi qu'à la durée de contraction. De plus, nous avons obtenu les courbes de pression-volume et avons estimé le rendement d'énergie du muscle en contraction active. Nous concluons d'après ces résultats que les propriétés du muscle du diaphragme n'éliminent pas son usage en tant que substituant du myocarde.

Zusammenfassung

Die mechanischen Eigenschaften von Zwerchfellmuskeln von Hunden wurden gemessen. Ein Teil des Zwerchfells wurde isoliert und zu einer Tasche geformt, die wiederum an verschiedene hydraulische Kreisläufe angeschlossen wurde. Wir maßen die Druckreaktion auf elektrische Stimulation durch verschiedene Spannungen, Frequenzen und Meßbasisdrücke, ferner die Kontraktionszeit. Wir erhielten ferner Druck-Volumen-Kurven und schätzten die abgegebene Leistung des aktiv kontrahierenden Muskels. Wir schlossen aus den Ergebnissen, daß die Eigenschaften des Zwerchfellmuskels seinen Gebrauch als Ersatz für den Herzmuskel nicht ausschließen.

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Vachon, B.R., Kunov, H. & Zingg, W. Mechanical properties of diaphragm muscle in dogs. Med. & biol. Engng. 13, 252–260 (1975). https://doi.org/10.1007/BF02477736

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  • DOI: https://doi.org/10.1007/BF02477736

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