Summary
Consecutive sections of certain neurons in the central ganglia of the pond snail Lymnaea stagnalis appear to be immunoreactive to anti-dopamine and anti-serotonin. The Cerebral Giant Neurons stain in addition with antivasotocin. The observations indicate the presence of two biogenic amines within the same neuron and in addition their co-existence with a biologically active peptide.
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References
Benjamin PR (1983) Gastropod feeding: behavioural and neural analysis of a complex multicomponent system. In: Roberts A, Roberts B (eds) Neural origin of rhythmic movements. Soc Exp Biol Symp XXXII, pp 159–193
Boer HH, Schot LPC (1983) Phylogenetic aspects of peptidergic systems. In: Lever J, Boer HH (eds) Neuro-endocrinology. Mon Kon Ned Akad Wet. North Holland Publ Co, Amsterdam, Oxford, New York, pp 9–14
Burnstock G (1976) Do some nerve cells release more than one transmitter? Neuroscience 1:239–248
Geraerts WPM, Tensen CP, Hogenes ThM (1983) Multiple release of peptides by electrically active neurosecretory Caudo-Dorsal Cells of Lymnaea stagnalis. Neurosci Lett 41:151–155
Goldschmeding JT, Duivenboden YA van, Lodder JC (1981) Axonal branching pattern and coupling mechanisms of the cerebral giant neurones in the snail Lymnaea stagnalis. J Neurobiol 12:405–424
Joosse J, Vlieger TA de, Roubos EW (1982) Nervous systems of lower animals as models, with particular reference to peptidergic neurons in gastropods. In: Buijs RM, Pevet P, Swaab DF (eds) Chemical transmission in the brain, Progress in Brain Research. Elsevier Biomedical Press, Amsterdam
Kerkut GA, Sedden CB, Walker RJ (1967) Uptake of DOPA and 5-hydroxytryptophane by monoamine forming neurones in the brain of Helix. Comp Bioch Physiol 23:159–162
Lundberg JH, Hökfelt T (1983) Co-existence of peptides and classical neurotransmitters. Trends in Neuroscience 6:325–333
Schot LPC (1984) Immunocytochemical studies on peptidergic neurons in the pond snail Lymnaea stagnalis. PhD thesis, Free University, Amsterdam, pp 1–96
Schot LPC, Boer HH (1982) Immunocytochemical demonstration of peptidergic cells in the pond snail Lymnaea stagnalis with an antiserum to the molluscan cardio-active tetrapeptide FMRFamide. Cell Tissue Res 225:347–354
Schot LPC, Boer HH, Swaab DF, Noorden S van (1981) Immunocytochemical demonstration of peptidergic neurons in the central nervous system of the pond snail Lymnaea stagnalis with antisera raised to biologically active peptides of vertebrates. Cell Tissue Res 216:273–291
Steinbusch WHM, Tilders FJH (1984) Localization of dopamine, noradrenalin, adrenalin, serotonin and histamine in the central nervous system. A light-microscopical immunohistochemical study. In: Furness J, Costa M (eds) IBRO-Handbook Series: Methods in neuroscience, vol. 6. Histochemical and ultrastructural identification of monoamine neurons. Wiley and Sons, Chichester, U.K. (in press)
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Boer, H.H., Schot, L.P.C., Steinbusch, H.W.M. et al. Co-existence of immunoreactivity to anti-dopamine, anti-serotonin and anti-vasotocin in the cerebral giant neuron of the pond snail Lymnaea stagnalis . Cell Tissue Res. 238, 411–412 (1984). https://doi.org/10.1007/BF00217315
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DOI: https://doi.org/10.1007/BF00217315