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A novel sequence polymorphism in the promoter region of the human B2-bradykinin receptor gene

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Abstract

The distribution of a nucleotide polymorphism in the core promoter of the human B2-bradykinin receptor gene was examined in the population of southern Germany. The allelic frequencies were 0.595 for the C allele and 0.405 for the T allele. The allelic frequencies were in Hardy-Weinberg equilibrium. This new marker provides a valuable tool to assess the risk for putative bradykinin-associated disorders with genetic determinism.

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References

  • Braun A, Kammerer S, Böhme E, Miller B, Roscher AA (1995a) Identification of polymorphic sites of the human bradykinin B2 receptor gene. Biochem Biophys Res Commun 211:234–240

    Google Scholar 

  • Braun A, Ambach H, Bichlmaier R, Kammerer S, Roscher AA (1995b) Population study of a sequence polymorphism in intron 2 of the human β-globin gene. Hum Genet 95:352

    Google Scholar 

  • Kammerer S, Braun A, Arnold N, Roscher AA (1995) The human bradykinin B2 receptor gene: full length cDNA, genomic organization and identification of the regulatory region. Biochem Biophys Res Commun 211:226–233

    Google Scholar 

  • Lindpainter K (1994) Genes, hypertension and cardiac hypertrophy. N Engl J Med 330:1678–1679

    Google Scholar 

  • Müller B, Clerget-Darpoux F (1991) A test based on the exact probability distribution of the chi-square statistic-incorporation into the MASC method. Ann Hum Genet 55:69–75

    Google Scholar 

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Braun, A., Maier, E., Kammerer, S. et al. A novel sequence polymorphism in the promoter region of the human B2-bradykinin receptor gene. Hum Genet 97, 688–689 (1996). https://doi.org/10.1007/BF02281884

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  • DOI: https://doi.org/10.1007/BF02281884

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