Summary
188 blood samples from Batak of Samosir Island (Sumatra, Indonesia) have been studied for electrophoretic variants of haemoglobin, 14 red cell enzyme and 5 serum protein systems. The acid phosphatase, 6 PGD, PGM1 and ADA enzyme systems are polymorphic, and a single AK 2-1 person was detected. Polymorphism is present in the haptoglobin, transferrin and protease inhibitor systems. Two variant alleles, Tf Dchi and Tf B are present in the transferrin system, but the B variant has not been identified. Similarly, 3 persons with caeruloplasmin variants were found, but also these variants have not been identified. No abnormal haemoglobins were detected. All other systems revealed the presence of only normal phenotypes.
Zusammenfassung
188 Blutproben des Batak-Stammes von Samosir Island (Sumatra, Indonesien) wurden auf elektrophoretische Varianten des Hämoglobins in 14 Erythrocyten-enzym-und 5 Serumprotein-Systemen untersucht. Die Saure Phosphatase, 6GPD, PGM1 und ADA-Systeme sind polymorph, und eine einzige AK 2-1-Person wurde gefunden. In den Haptoglobin-, Transferrin- und Pi-Systemen treten Polymorphismen auf. Zwei abweichende Allele, Tf Dchi und Tf B, sind im Transferrin-System zu finden, aber die B-Variante ist nicht bestimmt worden. Ebenso wurden 3 Personen mit Ceruloplasmin-Varianten gefunden, doch auch diese Varianten wurden nicht identifiziert. Keine abnormen Hämoglobine wurden gefunden. Alle anderen Systeme wiesen nur normale Phenotypen auf.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Blake, N. M., Kirk, R. L., McDermid, E. M., Omoto, K., Ahuja, Y. R.: The distribution of serum protein and enzyme group systems among North Indians. Hum. Hered. 21, 440–457 (1971).
Chan, K. L.: Human red cell adenylate kinase polymorphism in West Malaysian populations. Hum. Hered. 21, 173–179 (1971).
Cunningham, C. E.: The post war migration of the Toba-Batak to East Sumatra. Yale University. South East Asia Studies Series (1958).
Heide, H. M., Van der: An analysis of blood grouping data collected in Indonesia and in the Netherlands. Publication No. 67 of the Nederlands Museum Voor Anthropologie and Department of Anthropology of the Royal Tropical Institute, Amsterdam, pp. 5–27 (1963).
Kirk, R. L.: The haptoglobin groups in man. Monographs in human genetics, No. 4. Basel: Karger 1968.
Kirk, R. L., Lai, L. Y. C.: The distribution of haptoglobin and transferrin groups in South and South Asia East. Acta genet. (Basel) 11, 97–105 (1961).
Kirk, R. L., McDermid, E. M., Blake, N. M., Wight, R. L., Yap, E. H., Simons, M. J.: The distribution of red cell enzyme and serum protein groups in a population of Dani (Pit River, West Irian). Humangenetik 17, 345–350 (1973).
Kirkman, H. N., Lie-Injo, Luan Eng: Variants of glucose-6-phosphate dehydrogenase in Indonesia. Nature (Lond.) 221, 959–960 (1969).
Lai, L. Y. C., Kariks, J.: Red cell acid phosphatases in the Baining population of New Britain (New Guinea). Archaeol. Phys. Anthrop. Oceania 3, 143–145 (1968).
Lai, L. Y. C., Kwa, S. B.: Red cell acid phosphatase types in some populations of South East Asia. Acta genet. (Basel) 18, 45–54 (1968).
Lie-Injo, Luan Eng: Distribution of genetic red cell defects in South East Asia. Trans. roy. soc. trop. med. Hyg. 63, 664–674 (1969).
Lie-Injo, Luan Eng, Chin, J., Ti, T. S.: Glucose-6-phosphate dehydrogenase deficiency in Brunei, Sabah and Sarawak. Ann. hum. Genet. 28, 173–176 (1964).
Lie-Injo, Luan Eng, Poey-Oey, Hoey Giok: Phosphoglucomutase, carbonic anhydrase and catalase in Indonesians. Hum. Hered. 20, 215–219 (1970).
Malcolm, L. A., Woodfield, D. G., Blake, N. M., Kirk, R. L., McDermid, E. M.: The distribution of blood, serum protein and enzyme groups on Manus (Admiralty Islands, New Guinea). Hum. Hered. (in press, 1972).
Omoto, K.: The distribution of red cell adenosine deaminase phenotypes in Oceania. Jap. J. hum. Genet. 16, 166–169 (1972).
Simmons, R. T., Graydon, J. J.: A comparison of the blood groups, subgroups, M-N and Rh types found in Java with those found in other parts of Indonesia, together with a summary of the evidence for north-south gradients in the values for the blood genes, q,m, and R1. Med. J. Aust. 1, 173–179 (1951).
Sinnett, P., Blake, N. M., Kirk, R. L., Lai, L. Y. C., Walsh, R. J.: Blood serum protein and enzyme groups among Enga-speaking people of the Western Highlands, New Guinea, with an estimate of genetic distance between clans. Archaeol. Phys. Anthrop. Oceania 5, 236–252 (1970).
Welch, Q. B., Lie-Injo, Luan Eng, Bolton, J. M.: Adenylate kinase and malate dehydrogenase in four Malaysian racial groups. Humangenetik 14, 61–63 (1971).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McDermid, E.M., Blake, N.M., Kirk, R.L. et al. The distribution of serum protein and enzyme groups among the Batak of Samosir Island (Sumatra, Indonesia). Hum Genet 17, 351–356 (1973). https://doi.org/10.1007/BF00273192
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00273192