Summary
The chromosome which carries the mutationsexcombless (In(1)sx) affects males and females ofD. melanogaster. In the male foreleg basitarsi the number of sexcomb teeth is dramatically reduced from 10 to 0.7 and the number of transverse rows of bristles is increased from 6 to 8. Females homozygous forIn(1)sx show a normal bristle pattern in the foreleg basitarsus. The genital disc derivatives of both male and femaleIn(1)sx flies are strongly affected. While the external genitalia show a duplicated or a reduced bristle pattern, the internal genitalia are mostly absent. However, the sexually dimorphic tergites and sternites of the abdomen remain unaffected. The male-specific effect on the basitarsus and the general effects on the genital disc derivatives are proposed to represent two different phenotypic effects ofIn(1)sx which may derive from mutations at different gene loci in the inverted chromosome.
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References
Baker BS, Ridge KA (1980) Sex and the single cell. I. On the action of major loci affecting sex determination inDrosophila melanogaster. Genetics 94:383–423
Bryant PJ, Hsei BW (1977) Pattern formation in asymmetrical and symmetrical imaginal discs ofDrosophila melanogaster. Am Zool 17:595–611
Davis BK (1971) Genetic analysis of a meiotic mutant resulting in precocious sister-centromere separation inDrosophila melanogaster. Molec Gen Genet 113:251–272
Denell RE, Jackson J (1972) A genetic analysis of transformerdominant. Drosoph Inform Serv 48:45
Dübendorfer K, Nöthiger R (1982) A clonal analysis of cell lineage and growth in the male and female genital disc ofDrosophila melanogaster. Wilhelm Roux's Arch (in press)
Ehrensperger P (1972) Transplantationsexperimente und Entwicklungsbeobachtungen in situ zur Bestimmung des dreidimensionalen Analageplanes der männlichen Genital-Imaginal-scheibe vonDrosophila melanogaster Diplomarbeit, University of Zürich, Switzerland
Epper F (1980) The genital disc ofDrosophila melanogaster. A developmental and genetic analysis of its sexual dimorphism. Ph.D. Thesis, University of Zürich, Switzerland
Epper F (1981) Morphological analysis and fate map of the intersexual genital disc of the mutantdoublesex-dominant inDrosophila melanogaster. Dev Biol 88:104–114
Epper F, Nöthiger R (1982) Genetic and developmental evidence for a repressed genital primordium inDrosophila melanogaster. Dev Biol (in press)
Goldschmidt R (1949) TheBeaded-Minute intersexes inDrosophila melanogaster Meigen. J Exp Zool 112:233–301
Gowen JW (1942) Hermaphrodites inDrosophila melanogaster. Drosoph Inform Serv 16:63
Hannah-Alava A (1958) Morphology and chaetotaxis of the legs ofDrosophila melanogaster. J Morphol 103:281–310
Kroeger H (1960) Hypo- and hyperdevelopment of the male genital apparatus and theBd-M combination inDrosophila melanogaster. J Morphol 107:227–232
Lindsley DL, Grell EH (1968) Genetic variations ofDrosophila melanogaster. Carnegie Inst. Washington Publ No 627
Littlefield CL, Bryant PJ (1979) Prospective fates and regulative capacities of fragments of the female genital disc ofDrosophila melanogaster. Dev Biol 70:127–148
Mukherjee AS (1963) Some cytological information about the mutant “sexcombless” inDrosophila melanogaster. Drosophila Inform Serv 38:62
Mukherjee AS (1965) The effects of “sexcombless” on the forelegs ofDrosophila melanogaster. Genetics 51:285–304
Stern C (1941) The growth of testes inDrosophila I. The relation between vas deferens and testis within various species. J Exp Zool 87:113–138
Sturtevant AH (1945) A gene inDrosophila melanogaster that transforms females into males. Genetics 30:297–299
Tokunaga Ch (1962) Cell lineage and differentiation on the male foreleg ofDrosophila melanogaster. Dev Biol 4:489–516
Wieschaus E, Nöthiger R (1982) The role of the “transformet” genes in the development of genitalia and analia ofDrosophila melanogaster. Dev Biol (in press)
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Reinhardt, C.A., Sanchez, L. Effects of the “sexcombless” chromosome (In(1)sx) on males and females ofDrosophila melanogaster . Wilhelm Roux' Archiv 191, 264–269 (1982). https://doi.org/10.1007/BF00848414
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DOI: https://doi.org/10.1007/BF00848414