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Histochemical evidence of monoamine oxidase activity in rats of different ages

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Summary

The histochemically detectable monoamine oxidase activity in certain organs of young and old rats is compared. Regardless of age, the activity is strong in the liver, faint in the skeletal muscle, and absent in the kidney. In the myocardium, however, the quantity of monoamine oxidase increases strongly with age. Its activity is manifest in the form of granular and diffuse formazan precipitates; both disappear after a preliminary treatment of the animals with a monoamine oxidase inhibitor. This finding indicates that the diffuse as well as the previously identified granular precipitates represent monoamine oxidase.

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Studer, A., Baumgartner, H.R. & Reber, K. Histochemical evidence of monoamine oxidase activity in rats of different ages. Histochemie 4, 43–47 (1964). https://doi.org/10.1007/BF00304177

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  • DOI: https://doi.org/10.1007/BF00304177

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