Summary
The structure and behavior of XY bivalent in mice is discussed. The view that XY bivalent in pachytene is embedded within the sex vesicle was fully confirmed. X and Y are paired end-to-end by a nonchiasmatic connection, which is established already in pachytene and persists until first meiotic metaphase. The pachytene complement in mice consists of 19 rod-shaped autosomal bivalents and the XY bivalent embedded within the sex vesicle. A satisfactory identification of individual autosomes in male pachytene has not been found possible.
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Crew, F. A. E., and P. C. Koller: The sex incidence of chiasma frequency and genetical crossing-over in the mouse. J. Genet. 26, 359–383 (1932).
Dunn, L. C., D. Bennett and A. B. Beasley: Mutation and recombination in the vicinity of a complex gene. Genetics 47, 285–303 (1962).
Griffen, A. B.: A late pachytene chromosome map of the male mouse. J. Morph. 96, 123–136 (1955); - Mammalian pachytene chromosome mapping and somatic chromosome identification. J. cell. comp. Physiol. 56, Suppl. 1, 113–121 (1960).
Koller, P. C., and C. D. Darlington: The genetical and mechanical properties of sex chromosomes. I. Rattus norvegicus. J. Genet. 29, 159–173 (1934).
Makino, S.: Studies on the murine chromosomes. I. Cytological investigations of mice included in the genus Mus. J. Fac. Sci. Hokkaido Imp. Univ., Ser VI Zool. 7, 305–380 (1941).
Matthey, R.: Les Chromosomes des vertébrés. Lausanne: F. Rouge 1949; - Les chromosomes des Muridae. Rev. suisse Zool. 60, 225–283 (1953).
Oguma, K.: On the sex chromosomes of rats and mice. Proc. Jap. Ass. Adv. Sci. 10, 143–146 (1935) [in Japanese].
Ohno, S., W. D. Kaplan and R. Kinosita: Heterochromatic regions and nucleolus organizers in chromosomes of the mouse, Mus musculus. Exp. Cell Res. 13, 358–364 (1957); - On the end-to-end association of the X and Y chromosomes of Mus musculus. Exp. Cell Res. 18, 282–290 (1959a); - Do XY sperm occur in Mus musculus? Exp. Cell Res. 18, 382–384 (1959b).
—, and C. Weiler: Sex chromosomes behavior pattern in germ and somatic cells of Mesocricetus auratus. Chromosoma (Berl.) 12, 363–373 (1961).
Painter, T. S.: The chromosome constitution of Gates' “nondisjunction” (v-o) mice. Genetics 12, 379–392 (1927).
Slizynski, B. M.: A preliminary pachytene chromosome map of the house mouse. J. Genet. 49, 242–245 (1949);- The sex bivalent of Mus musculus L. J. Genet. 53, 591–596 (1955a); - Chiasmata in the male mouse. J. Genet. 53, 597–605 (1955b); - Sexual dimorphism in mouse gametogenesis. Genet. Res. 1, 477–486 (1960).
Stich, H. F., and T. C. Hsu: Cytological identification of male and female somatic cells in mouse. Exp. Cell Res. 20, 248–249 (1960).
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This paper is dedicated to Professor L. C. Dunn on the occasion of his retirement as Professor from Columbia University in recognition of his deep humanity as a scientist and a man.
Research carried out under a fellowship of the Rockefeller Foundation, and later under fellowship support of the U. S. Department of Health, Education and Welfare through a training grant to the Department of Zoology, Columbia University. The experiments were supported financially by Contract AT/30-1/1804 with the U. S. Atomic Energy Commission.
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Geyer-Duszyńska, I. On the structure of the XY bivalent in Mus musculus L.. Chromosoma 13, 521–525 (1962). https://doi.org/10.1007/BF00321161
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DOI: https://doi.org/10.1007/BF00321161