Skip to main content
SpringerLink
Log in

The nucleotide excision repair epistasis group in Neurospora crassa

  • Original Articles
  • Published:
Current Genetics Aims and scope Submit manuscript

Summary

DNA repair mutants in eucaryotes are normally assigned to three epistasis groups. Each epistasis group represents a “pathway” for DNA repair. The pathways are commonly designated (1) nucleotide excision repair, (2) recombination repair and (3) mutagenic repair. An excision repair epistasis group has been established in Neurospora and the mutants assigned to this group should be limited in their ability to excise pyrimidine dimers and other bulky lesions from DNA. Using a pyrimidine dimer-specific assay, we have found that all Neurospora crassa mutants assigned to the excision repair epistasis group are capable of removing pyrimidine dimers from the DNA at a rate similar to the wild-type organism.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Baker TI (1983) Mol Gen Genet 190:295–299

    Google Scholar 

  • deSerres FJ (1980) Mutation Res 71:181–191

    Google Scholar 

  • Franklin WA, Haseltine WA (1984) Proc Natl Acad Sci USA 81:3821–3824

    Google Scholar 

  • Haynes RH, Kunz BA (1981) In: Strathern JN, Jones EW, Broach JR (eds) The molecular biology of the yeast Saccharomyces: Life cycle and inheritance. Cold Spring Harbor Laboratory Cold Spring Harbor, New York, pp 371–414

    Google Scholar 

  • Howard CA, Baker TI (1986) Mol Gen Genet 203:462–467

    Google Scholar 

  • Howard CA, Baker TI (1989) Curr Genet 15:47–55

    Google Scholar 

  • Kafer E (1983) Genetics 105:19–33

    Google Scholar 

  • Macleod H, Stadler D (1986) Mol Gen Genet 202:321–326

    Google Scholar 

  • Mitchel REJ, Morrison DP (1987) Mutation Res 183:149–159

    Google Scholar 

  • Schroeder AL (1974) Mutation Res 24:9–16

    Google Scholar 

  • Stadler D (1983) Mol Gen Genet 190:227–232

    Google Scholar 

  • Stadler D, Moyer R (1981) Genetics 98:763–774

    Google Scholar 

  • Worthy TE, Epler JL (1973) Mutation Res 19:167–173

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Microbiology, School of Medicine, University of New Mexico, 87131, Albuquerque, NM, USA

    T. I. Baker, C. E. Cords, C. A. Howard & R. J. Radloff

Authors
  1. T. I. Baker
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. E. Cords
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. A. Howard
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. J. Radloff
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by R. H. Haynes

Rights and permissions

Reprints and permissions

About this article

Cite this article

Baker, T.I., Cords, C.E., Howard, C.A. et al. The nucleotide excision repair epistasis group in Neurospora crassa . Curr Genet 18, 207–209 (1990). https://doi.org/10.1007/BF00318382

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00318382

Key words

Search

Navigation