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Self-assembling functionalized templates in biosensor technology

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Abstract.

A bifacial topological template exhibiting metal-binding sites and thioalkane chains has been incorporated into self-assembled monolayers and immobilised on gold surfaces: These systems allow for the detection of external ligands by SPR spectroscopy representing a first step in developing biosensors based on the TASP (Template Assembled Synthetic Proteins) concept.

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Authors and Affiliations

  1. Institute of Organic Chemistry, University of Lausanne, BCH-Dorigny, CH-1015 Lausanne, Switzerland, , , , , , CH

    L. Scheibler, P. Dumy & M. Mutter

  2. Swiss Federal Institute of Technology, CH-1015 Lausanne, Switzerland, , , , , , CH

    D. Stamou, C. Duschl & H. Vogel

Authors
  1. L. Scheibler
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  2. P. Dumy
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  3. D. Stamou
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  4. C. Duschl
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  5. H. Vogel
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  6. M. Mutter
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Additional information

Received: 17 November 1997/Accepted: 12 December 1997

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Scheibler, L., Dumy, P., Stamou, D. et al. Self-assembling functionalized templates in biosensor technology. Polymer Bulletin 40, 151–157 (1998). https://doi.org/10.1007/s002890050236

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  • DOI: https://doi.org/10.1007/s002890050236

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