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Mixtures of lecithin with polymerizable derivatives of cholesterol

A monolayer film balance study

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Abstract

One of the best investigated binary lipid mixtures is the lecithin-cholesterol system. We show here that it is possible to modify the cholesterol in such a way that it can be polymerized without changing its behaviour in mixtures with lecithin. The polymerizable derivatives exhibit a very similar phase diagram in the mixture with dipalmitoyl-phosphatidylcholine as the cholesterol itself. This is demonstrated by filmbalance measurements.

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Albrecht, O., Prass, W. & Ringsdorf, H. Mixtures of lecithin with polymerizable derivatives of cholesterol. Eur Biophys J 14, 97–102 (1986). https://doi.org/10.1007/BF00263066

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  • DOI: https://doi.org/10.1007/BF00263066

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