Summary
A randomized, double-blind clinical trial in 50 patients was done to compare the efficacy and tolerance of single doses of intramuscular diclofenac 75 mg and dipyrone 2 g in acute renal colic.
Both drugs were equally effective, but diclofenac was better in terms of complete relief of pain. Vital signs were affected according to the stress and pain.
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References
The International Agranulocytosis and Aplastic Anemia Study (1986) Risks of agranulocytosis and aplastic anemia: A first report of their relation to drug use with special reference to analgesics. J Am Med Assoc 256: 1749–1757
Lundstam S, Wahlander L, Leissner KH, Kral JG (1982) Prostaglandine-synthetase inhibition with diclofenac sodium in treatment of renal colic: comparison with use of a narcotic analgesic. Lancet 1: 1096–1097
Vignoni A, Fierro A, Moreschini G, Cau M, Agostino A, Daniele E, Foti G (1983) Diclofenac sodium in ureteral colic: Double-blind comparison trial with placebo. J Int Med Res 11: 303–307
Hetherington JW, Philp NH (1986) Diclofenac sodium versus pethidine in acute renal colic. Br Med J 292: 237–238
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Miralles, R., Camí, J., Gutiérrez, J. et al. Diclofenac versus dipyrone in acute renal colic: A double-blind controlled trial. Eur J Clin Pharmacol 33, 527–528 (1987). https://doi.org/10.1007/BF00544249
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DOI: https://doi.org/10.1007/BF00544249